DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mhcl and F28E10.4

DIOPT Version :9

Sequence 1:	NP_732109.2	Gene:	Mhcl / 41955	FlyBaseID:	FBgn0026059	Length:	2194	Species:	Drosophila melanogaster
Sequence 2:	NP_500590.2	Gene:	F28E10.4 / 185067	WormBaseID:	WBGene00017902	Length:	324	Species:	Caenorhabditis elegans

Alignment Length:	186	Identity:	39/186 - (20%)
Similarity:	72/186 - (38%)	Gaps:	40/186 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly  1948 GDPSMAM------MSKRLELRTKELESRLELEQATRARLEVQVNR-----HKEALEKLQNEVTQS 2001
            ||..|.|      |:...:...:|..|||    :|.|::...|.|     ..:..:|....:|..
Worm   163 GDSIMDMSGAPIPMTDNPDNFIREHLSRL----STGAKVSFLVERPISVAMAKQYQKFIESITYD 223

  Fly  2002 KMREMQAQDVIKKSQKSLRDMREEFHAVSSREQESLTRRKDLEKKVEQMESEGAALKNDLRLALQ 2066
            ......|||||:..:::     ...|.:.            |:|.|..     :.|.:|:|  .:
Worm   224 DSEVEMAQDVIEIGREA-----SNMHFMI------------LKKLVTP-----SILSSDVR--RR 264

  Fly  2067 RIADLQQAMEEEGEEELSESDESLSSVGSISDLEDRLRPVHVKRSSQQSLNGSIGG 2122
            :.::.:.:...||...:|.:...:.....::|.:| |:||..|..:..|.:...||
Worm   265 KKSNNKTSESTEGSITISSASTEMKITSDVTDFDD-LKPVESKSHAAGSSSSDSGG 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID
Mhcl	NP_732109.2	PDZ_signaling	339..426	CDD:238492
		MYSc	556..1317	CDD:214580
		MYSc_Myo18	575..1305	CDD:276837
		GBP_C	<1540..1750	CDD:303769
		COG1340	1565..1833	CDD:224259
		coiled coil	1723..1734	CDD:293879
F28E10.4	NP_500590.2	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900