Protein Alignment Mhcl and T19B10.5

DIOPT Version :9

• Sequence 1: NP_732109.2
• Gene: Mhcl / 41955
• FlyBaseID: FBgn0026059
• Length: 2194
• Species: Drosophila melanogaster
• Sequence 2: NP_505852.3
• Gene: T19B10.5 / 179553
• WormBaseID: WBGene00011833
• Length: 596
• Species: Caenorhabditis elegans
• Alignment Length: 601
• Identity: 112/601 - (18%)
• Similarity: 199/601 - (33%)
• Gaps: 187/601 - (31%)

  Fly    45 SMSTDELLRLDEVRRSLKIRGRRKEKEKLPSGITADYSADFFAALNADANGGSNGGAVGAADPE- 108
            |::.|::..:|    |.|::.:.::     ||....||.:|...:.........|..:|.....
 Worm    88 SINKDKMTMID----SFKLKRKMED-----SGTQKAYSMEFLNEVEGKVGVQLRGVDIGGLGFNI 143

  Fly   109 QDRGNEEIVAS--VMTHIESRASN---G---AGVSVNYSEVTH----SLLSGGLKNRFLPPIPPK 161
            |...||.|...  :...|..:..|   |   ..:::|:..:.:    :|||      :..|...|
 Worm   144 QGNMNEGIFVKEIISKGIAEQCGNILVGDKIKSLTINFENMVYEDAVTLLS------YSSPYKVK 202

  Fly   162 PPKRGILKGSRSNMTNVHEEISFAGSAGGAGGTPEMLLRNTFQNESLYEGAARGAGSIGSNSSQH 226
                          ..:..::|.:.|...:....||.....|::.:|........|:|.:.:|
 Worm   203 --------------LELERKLSDSASVSDSDDDKEMRYHPLFRSNTLTHVHFNPLGTISTPTS-- 251

  Fly   227 GTSFTSVESLRSDGEQTGG--QQRAMTLP-----ANARYGALPQGNSQGSHLHVLTSPSPSADSL 284
             .:.|......:|.:|...  .||.:..|     |:....|....||:      :.|....:|.:
 Worm   252 -IATTPQRCTSTDSKQKHALPPQREIIEPDSTTCADDNSQARDADNSR------MDSSDYGSDGI 309

  Fly   285 TDTTNSSFATPPFSLSPVGESQGIDRWA--RVHA----FEDVELPLPP-----VQLVKLPP-PRQ 337
            :|...|:            .|.|..:..  |:..    |:.|:.|.||     .|..:||| ||:
 Worm   310 SDCREST------------ASDGTQKTLSDRIEVTDIIFDKVKSPTPPPLRKLEQCTELPPKPRK 362

  Fly   338 LVIRRQK-------SPRQDFGFSLRKAICLD---------------RTESLTSPIFRPVIFAEPG 380
            :|.|...       ||:.....|.:|:..::               :||...:|:..|:
 Worm   363 MVSRSPSPVNKPPPSPKVSRATSPKKSQQVEDSTQTTQLSAETRPTQTEKPIAPVPPPI------ 421

  Fly   381 AGGGATGLLPGDRLIKV-NGTPVGELPREIIIEMIRNSGEAVTVEVQPV--------------AE 430
                  ..:|..:.::. ..||.   |.:.::|.|        ||:.||              |.
 Worm   422 ------SSIPVRKEMETQTKTPP---PDQTVVEKI--------VEIAPVEIKEDDSKGPEITEAR 469

  Fly   431 LVELSKRCMAPSTATVE----EIDHSITNGNCNTLRRSASKR---FKRQSRHENGNGGGEEGGAK 488
            :..:.||..:..|..:|    .:..|:|..:     .||.|.   :.|..:.:.||
 Worm   470 ISRIPKRSDSIKTPVIERKLPSLPKSVTQRS-----HSADKNDNVWSRLYQEKKGN--------- 520

  Fly   489 GVGHDLEADVADASQPERVWLVHRGGFTAAIR-----LPTASSGR----DEENKLSL------RL 538
                  .....|.|.|.   ..|..|.....|     ..||:.|:    |.|...:|      ||
 Worm   521 ------LRKTRDVSSPP---TAHTSGIPTPSRSSITSTVTATVGKTPSTDNEKYGTLTREKRDRL 576

  Fly   539 LHNGEQLTVDEDDVEK 554
            :.|..:|....:::.|
 Worm   577 MANDAELERQREELRK 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mhcl	NP_732109.2	PDZ_signaling	339..426	CDD:238492	18/109 (17%)
		MYSc	556..1317	CDD:214580
		MYSc_Myo18	575..1305	CDD:276837
		GBP_C	<1540..1750	CDD:303769
		COG1340	1565..1833	CDD:224259
		coiled coil	1723..1734	CDD:293879
T19B10.5	NP_505852.3	PDZ	137..208	CDD:214570	14/90 (16%)
		PTZ00449	<340..483	CDD:185628	32/165 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900