| Sequence 1: | NP_732109.2 | Gene: | Mhcl / 41955 | FlyBaseID: | FBgn0026059 | Length: | 2194 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_071855.2 | Gene: | Myh9 / 17886 | MGIID: | 107717 | Length: | 1960 | Species: | Mus musculus |
| Alignment Length: | 2057 | Identity: | 522/2057 - (25%) |
|---|---|---|---|
| Similarity: | 864/2057 - (42%) | Gaps: | 560/2057 - (27%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 499 ADASQPERVWL-VHRGGFTAAIRLPTASSGRDEENKLSL-RLLHNGEQLTVDEDDVEKQNSPALD 561
Fly 562 LVEDICELKYLNEASVLHCLRQRYASNLIHTKAGPTLLVVNPMAPLSLYSEKVVSMFRGCKTEDM 626
Fly 627 PPHVYSLAQTAYRSLVETRRDQSLIFMGRSGSGKSTSFKHALNYLALAAGAYNN----------F 681
Fly 682 INAEKVNALCTILEAFGNTKTCLNSNATRMTQLLSLDFDQTGQIASASLQVLLPERQRAGRRLGH 746
Fly 747 EHSFHIMTRLLAGAAGLLQKELHLENITSEDSHPFISLSQKLEDRHRAANDFMRTVQAFETLNID 811
Fly 812 AKAVRGIWSILAAIYHLGIAGVTKLGTGSTARTQFANPTAARKASGLLGVNLEDLSSAAFGLTQP 876
Fly 877 NAPNGGLSPSKSPTSDTGHEWAWECLEALVIGLYSEALAAVVALINRQICTSSHTIAS-IMLIDT 940
Fly 941 PGFQNPASCGQQVGATLADLRH------NYLQERLQMLFHHTTLVAPRDRYAQE-----LVEIEM 994
Fly 995 DLASECHPGPLISLIDK--APQNHVVRSSQRDLREHDRRGMLWLLDEEAIYPNSNDDTFLERLFS 1057
Fly 1058 HYGDREHHSLLRKCAGPRQ------FVLHHLQGTNPVLYAVDGWVRHSREHPGIRNAVSLLQDSS 1116
Fly 1117 REEINRLYIGSLTRGSGAMVFCGSFAGLEGTQSLRRVSSIRRSFTTAGVKRNSIMLQV-KFTVDG 1180
Fly 1181 IIDTLRRTGTHFVHCYLLQH--NAGKHTKYTANGSPSSAAGQVSSEEEMVNVPLLRSQLRGSQVL 1243
Fly 1244 EAARLHRLGFPESVPLLEFVRRFGLLAGD-----LASNKDVSVEQILAVNELDVASYRIGPSQIL 1303
Fly 1304 FRSGVLSELEAKRDVLLSDRIIQLQAFCRGYLARKKMSQRRVQELAVRCIQRNVKAFLAVRDWPW 1368
Fly 1369 WRLLVRVTPLLNVHRTEEQLKTANEELLMLRAK-------LEKIECDRSEVKAENQKLEAKL--- 1423
Fly 1424 SELTVDLAEE---RSTA---------HIATERLEAE-------TAERLKLEKELGDQTNKVKNLQ 1469
Fly 1470 ETTEKLEMELICAKSDLNGISED------------------ED----------AENEDGVGGGVY 1506
Fly 1507 KLKYERVARELEFTKRRLHTQHEHDLEQLVALKKHLEMKLSDAYEEVVEQRQVVGQWKRKAQKMT 1571
Fly 1572 NEMNDLRMLLEEQNARNNLLEKKQRKFDAECQSLQDAVRQERQAKERYGREK----DVLQAEKFT 1632
Fly 1633 LEQTLADTRLDLEF---KEEKLASLQRELEE-------------MTFGGGTEE---EFAQLRRSK 1678
Fly 1679 NETERRAKEQEEELDEMAGQIQLLEQ-------------------------------------AK 1706
Fly 1707 LRLEM------------------------------TLETMRKEARRE-------SQQRD------ 1728
Fly 1729 ---EELEEVRGNGYKKIKALECQ--------------LETEHEERTLLLREKHELERRLSS---- 1772
Fly 1773 -----------------------------------------------------MEDRDRVDRDA- 1783
Fly 1784 -------------EEALNQK------------------------------LRRDLRKYKALLKDA 1805
Fly 1806 QTQLERL-------------------------KADTPG---------KTLIRQLRN---QLEDAE 1833
Fly 1834 SARSLAMKARQTAEAELTEVQAMFDESHRARNDAEE---RANAAHRD-----------RAELQAQ 1884
Fly 1885 IEENEEELGELMKKYSATVKQLNTEQINVSEAEFKLNEMEAERNNLKEQVAELQHRLDNVENLGD 1949
Fly 1950 PSMAMMSK-RLELRTKELESRLELEQAT---------RARLEV-QVN-----------RHKEALE 1992
Fly 1993 KL--QNEVTQSKMREMQA-------------QDVIKKSQKSLRDMREEFHAVSSREQESLTRRKD 2042
Fly 2043 LEKKVEQMESEGAALKNDLRLALQRIADLQQAMEEEGEE-------------ELSESDESLSSVG 2094
Fly 2095 -SISDLEDRLR----PVHVKR---------SSQQSLNGSIGG 2122 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Mhcl | NP_732109.2 | PDZ_signaling | 339..426 | CDD:238492 | |
| MYSc | 556..1317 | CDD:214580 | 240/798 (30%) | ||
| MYSc_Myo18 | 575..1305 | CDD:276837 | 223/767 (29%) | ||
| GBP_C | <1540..1750 | CDD:303769 | 62/329 (19%) | ||
| COG1340 | 1565..1833 | CDD:224259 | 92/525 (18%) | ||
| coiled coil | 1723..1734 | CDD:293879 | 5/26 (19%) | ||
| Myh9 | NP_071855.2 | Mediates interaction with LIMCH1. /evidence=ECO:0000250|UniProtKB:P35579 | 2..838 | 287/919 (31%) | |
| Myosin_N | 30..68 | CDD:280832 | 10/44 (23%) | ||
| Myosin_head | 83..764 | CDD:278492 | 231/779 (30%) | ||
| Motor_domain | 95..764 | CDD:277568 | 223/767 (29%) | ||
| Actin-binding | 654..676 | 7/21 (33%) | |||
| Myosin_tail_1 | 842..1921 | CDD:279860 | 224/1099 (20%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1035..1057 | 6/25 (24%) | |||
| UBAN | 1038..1149 | CDD:301588 | 25/114 (22%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1117..1167 | 13/49 (27%) | |||
| RRF | <1206..1261 | CDD:294170 | 10/54 (19%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1327..1352 | 6/24 (25%) | |||
| RILP-like | <1480..1587 | CDD:304877 | 15/106 (14%) | ||
| DUF2390 | <1610..1678 | CDD:295281 | 19/71 (27%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1768..1788 | 3/19 (16%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1877..1908 | 7/30 (23%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1939..1960 | 3/15 (20%) | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E2759_KOG0161 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||