DRSC/TRiP Functional Genomics Resources

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Protein Alignment Mhcl and gras-1

DIOPT Version :9

Sequence 1:NP_732109.2 Gene:Mhcl / 41955 FlyBaseID:FBgn0026059 Length:2194 Species:Drosophila melanogaster
Sequence 2:NP_492164.1 Gene:gras-1 / 172549 WormBaseID:WBGene00009272 Length:245 Species:Caenorhabditis elegans


Alignment Length:244 Identity:50/244 - (20%)
Similarity:97/244 - (39%) Gaps:57/244 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly  1900 SATVKQLNTEQINVSE--------AEFKLNEMEAER-NNLKEQVAELQHRLDNVENLGDPSMAMM 1955
            |::..:.:|...|:||        .|:.||:...:. |....|.:.|..|.....:.|....:.:
 Worm    13 SSSSSKYDTPDDNISEQRLLCDAKEEYPLNDYLFDGINQESAQRSLLLCRQTFETSFGFALQSYV 77

  Fly  1956 SKRLELRTKELESRLELEQA---------TRARLEVQVNRHKEALEKLQNEVTQSKMREMQA--- 2008
            .||....:.|..:.::...|         ||..:.:.|| .|..:.....|:.:|..:.:|.   
 Worm    78 FKRTSSNSYERITYVDYVSADSPADRCGITRGDMVIAVN-EKSVVTASHAEIVESIAQCLQVSLV 141

  Fly  2009 ---QDVIKKSQKSLRDMREEFHAVSSREQESLTRRKDLEKKVEQMESEGAALKNDLRLALQRIAD 2070
               :||.:..:.|:|.::..|.               |:.|:           .:||:..:...|
 Worm   142 LVFKDVARIVELSMRSIQLRFM---------------LDAKI-----------RELRMLEKTEED 180

  Fly  2071 LQQAMEEEGEEELSESDESLSSVGSISDLEDRLRPVHVKRSSQQSLNGS 2119
            ||...::|...|  |.||||.|  ::.:|::.|:  :|:...::..||:
 Worm   181 LQALYDDEHGNE--EEDESLES--TLYELDEELK--NVQNPQEKEANGT 223

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MhclNP_732109.2 PDZ_signaling 339..426 CDD:238492
MYSc 556..1317 CDD:214580
MYSc_Myo18 575..1305 CDD:276837
GBP_C <1540..1750 CDD:303769
COG1340 1565..1833 CDD:224259
coiled coil 1723..1734 CDD:293879
gras-1NP_492164.1 PDZ 67..145 CDD:238080 13/78 (17%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3528
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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