DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mhcl and LOC100537963

DIOPT Version :9

Sequence 1:	NP_732109.2	Gene:	Mhcl / 41955	FlyBaseID:	FBgn0026059	Length:	2194	Species:	Drosophila melanogaster
Sequence 2:	XP_003199443.3	Gene:	LOC100537963 / 100537963	-ID:	-	Length:	479	Species:	Danio rerio

Alignment Length:	315	Identity:	95/315 - (30%)
Similarity:	162/315 - (51%)	Gaps:	26/315 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   488 KGVGHDLEADVADASQPE--------------RVWLVHRGGFTAAIRL-PTASSGRDEENKLSLR 537
            |||..:.|..:......|              :||..|:.|:|.|.:| |...:....:.::.:|
Zfish   164 KGVRQEPEGQITVTHMKEESKVPVKDVWYEAGQVWFTHKDGYTLATQLKPDEGTPELPDGRVRVR 228

  Fly   538 LLHNGEQLTVDEDDVEKQNSPALDLVEDICELKYLNEASVLHCLRQRYASNLIHTKAGPTLLVVN 602
            |..:.....|.:.::||.|.|.|||.||:.:|..:||:|.||.|..|..::|..|.|||.||.:.
Zfish   229 LSSDQSIHDVSQYEIEKLNPPELDLCEDLSDLVSVNESSALHTLSSRAKAHLPLTHAGPNLLALW 293

  Fly   603 PMAPLSLYSEKVVSMFRGCKTE--DMPPHVYSLAQTAYRSLVETRRDQSLIFMGRSGSGKSTSFK 665
            |  |:|..::.    ||..:.|  :.|..:.::.:..|.|::..||||:|:.:|||||||:|:.:
Zfish   294 P--PVSSSTKS----FRSRRWESWEAPGPLQAVVRKVYVSMLGQRRDQTLVALGRSGSGKTTACQ 352

  Fly   666 HALNYLALAAGAYNNFINAEKVNALCTILEAFGNTKTCLNSNATRMTQLLSLDFDQTGQIASASL 730
            .....|...||.....:..|::.|:.|:|.:||...:..:..::|...:||:||:..|..|:|.|
Zfish   353 SFSLELLKQAGTAGGSLTLERLQAVFTVLRSFGCVSSTHSEASSRFAMVLSVDFNHAGLAAAAHL 417

  Fly   731 QVLLPERQRAGRRLGHEHSFHIMTRLLAGAAGLLQKELHLENITSEDSHPFISLS 785
            |.:|.|:.|..:|...|.:|.:.:::|:|.:..|:.||.|..:   ..|.|..::
Zfish   418 QTMLLEKWRVCQRPDGESNFLVFSQMLSGLSSDLRTELQLHQL---KEHNFFGIT 469

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mhcl	NP_732109.2	PDZ_signaling	339..426	CDD:238492
		MYSc	556..1317	CDD:214580	77/232 (33%)
		MYSc_Myo18	575..1305	CDD:276837	67/213 (31%)
		GBP_C	<1540..1750	CDD:303769
		COG1340	1565..1833	CDD:224259
		coiled coil	1723..1734	CDD:293879
LOC100537963	XP_003199443.3	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D23517at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010