DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sxe2 and Pnliprp1

DIOPT Version :9

Sequence 1:	NP_001287352.1	Gene:	sxe2 / 41954	FlyBaseID:	FBgn0038398	Length:	387	Species:	Drosophila melanogaster
Sequence 2:	NP_114470.1	Gene:	Pnliprp1 / 84028	RGDID:	620792	Length:	473	Species:	Rattus norvegicus

Alignment Length:	373	Identity:	109/373 - (29%)
Similarity:	158/373 - (42%)	Gaps:	61/373 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LWT-CLLLLGAA-GTDASVDYFAYAPGKCEVSISDVIQGMITTEAGVILGRPRPSQTKLLRYDLY 76
            ||| .|.||||| |.:...|...     | .|.::...|.......::...|....|:.|   ||
  Rat     4 LWTVSLFLLGAAQGKEVCYDNLG-----C-FSDAEPWAGTAIRPLKLLPWSPEKINTRFL---LY 59

  Fly    77 TPLNPEERQLLRPGDLTMLRNSHFNPKWPVRVSIHGWAGKSV------TCSNA-AIKDAYLSRGN 134
            |..||...|.|:..|...:..|:|......|..|||:..|..      .|.|. .:::.
  Rat    60 TNENPTAFQTLQLSDPLTIGASNFQVARKTRFIIHGFIDKGEENWVVDMCKNMFQVEEV------ 118

  Fly   135 YNVIILDWSRQSLDISYPRVSKQLPSIAANVAKMLRFLHDNTGVPYEQIYMIGHSAGSHISGLTG 199
             |.|.:||.:.| ..:|.:.:..:..:.|.||:|:..|..|......::::||||.|:|::|..|
  Rat   119 -NCICVDWKKGS-QTTYTQAANNVRVVGAQVAQMIDILVKNYSYSPSKVHLIGHSLGAHVAGEAG 181

  Fly   200 KLLRPHRLGAIFALDPAGLTQLSLGPEERLDVNDALYVESIHTD----LTLLGNPSTKLS-HASF 259
            .  |...||.|..|||..........|.|||.:||.:|:.||||    :..||..:.::| |..|
  Rat   182 S--RTPGLGRITGLDPVEANFEGTPEEVRLDPSDADFVDVIHTDAAPLIPFLGFGTNQMSGHLDF 244

  Fly   260 FANWGLGQPHCPNATATEF-----------DFV-CDHFAAMFYFAESVRQPKSFAALRCSSAKSV 312
            |.|.|...|.|.....::.           ||| |:|..:..|:.||:..|..|||..|:|.|..
  Rat   245 FPNGGQSMPGCKKNALSQIVDIDGIWSGTRDFVACNHLRSYKYYLESILNPDGFAAYPCASYKDF 309

  Fly   313 LSATC------NCNVGGSEKYAVNTCTGNEFMGGEPAVPKRGIFYLST 354
            .|..|      .|...|  .||      ::|.|.....|::  |:|:|
  Rat   310 ESNKCFPCPDQGCPQMG--HYA------DKFAGKSGDEPQK--FFLNT 347

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sxe2	NP_001287352.1	Lipase	53..360	CDD:278576	95/332 (29%)
sxe2	NP_001287352.1	Pancreat_lipase_like	72..356	CDD:238363	92/313 (29%)
Pnliprp1	NP_114470.1	Lipase	18..353	CDD:395099	99/359 (28%)
Pnliprp1	NP_114470.1	PLAT_PL	356..467	CDD:238857
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339020
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.840