DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sxe2 and Pnlip

DIOPT Version :9

Sequence 1:	NP_001287352.1	Gene:	sxe2 / 41954	FlyBaseID:	FBgn0038398	Length:	387	Species:	Drosophila melanogaster
Sequence 2:	NP_081201.2	Gene:	Pnlip / 69060	MGIID:	97722	Length:	465	Species:	Mus musculus

Alignment Length:	397	Identity:	113/397 - (28%)
Similarity:	166/397 - (41%)	Gaps:	96/397 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LLWTCLLLLGA-AGTDASVDYFAYAPGKCEVSISDVIQGMITTEA--GVILGRP------RPSQT 68
            :|||..:|||| ||.:...|..                |..:.:|  ...|.||      .|:|.
Mouse     3 MLWTFAVLLGAVAGREVCFDKL----------------GCFSDDAPWSGTLDRPLKALPWSPAQI 51

  Fly    69 KLLRYDLYTPLNPEERQLLRPGDLTMLRNSHFNPKWPVRVSIHGWAGK------SVTCSNAAIKD 127
            . .|:.|||..||:..||: ..|.:.:|||:|......|:.|||:..|      |..|.|....:
Mouse    52 N-TRFLLYTNENPDNYQLI-TSDASNIRNSNFRTNRKTRIIIHGFIDKGEENWLSDMCKNMFRVE 114

  Fly   128 AYLSRGNYNVIILDWSRQSLDISYPRVSKQLPSIAANVAKMLRFLHDNTGVPYEQIYMIGHSAGS 192
                  :.|.|.:||...| ..:|.:.::.:..:.|.||.::..|..:.|.....:::||||.||
Mouse   115 ------SVNCICVDWKGGS-RTTYTQATQNVRVVGAEVALLVNVLQSDLGYSLNNVHLIGHSLGS 172

  Fly   193 HISGLTGKLLRPH-RLGAIFALDPA-----GLTQLSLGPEE-RLDVNDALYVESIHTD----LTL 246
            ||:|..||  |.. .:|.|..||||     |.      ||| |||..||.:|::||||    :..
Mouse   173 HIAGEAGK--RTFGAIGRITGLDPAEPYFQGT------PEEVRLDPTDAQFVDAIHTDAGPIIPN 229

  Fly   247 LG-NPSTKLSHASFFANWGLGQPHCPN---ATATEFDFV---------CDHFAAMFYFAESVRQP 298
            || ..|..:.|..||.|.|:..|.|..   :...:.|.:         |:|..:..::.:|:..|
Mouse   230 LGFGMSQTVGHLDFFPNGGIEMPGCQKNILSQIVDIDGIWEGTRNFAACNHLRSYKFYTDSIVNP 294

  Fly   299 KSFAALRCSSAKSVLSATC-NCNVGG-------SEKYAVNTCTGNEFMGGEPAVPKR--GIFYLS 353
            ..||...|||.....:..| .|..||       :::|              |....|  ..|||:
Mouse   295 TGFAGFSCSSYSLFTANKCFPCGSGGCPQMGHYADRY--------------PGKTSRLYQTFYLN 345

  Fly   354 TRPQSPY 360
            |..:|.:
Mouse   346 TGDKSNF 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sxe2	NP_001287352.1	Lipase	53..360	CDD:278576	102/354 (29%)
sxe2	NP_001287352.1	Pancreat_lipase_like	72..356	CDD:238363	95/323 (29%)
Pnlip	NP_081201.2	Lipase	18..352	CDD:278576	104/380 (27%)
		Pancreat_lipase_like	51..348	CDD:238363	95/327 (29%)
		PLAT_PL	355..465	CDD:238857
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835412
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840