DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sxe2 and lipca

DIOPT Version :9

Sequence 1:	NP_001287352.1	Gene:	sxe2 / 41954	FlyBaseID:	FBgn0038398	Length:	387	Species:	Drosophila melanogaster
Sequence 2:	NP_957316.1	Gene:	lipca / 393997	ZFINID:	ZDB-GENE-040426-1361	Length:	514	Species:	Danio rerio

Alignment Length:	368	Identity:	97/368 - (26%)
Similarity:	146/368 - (39%)	Gaps:	76/368 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 CEVSISDVIQGMITTEAGVILGR---PRPSQTKLLRYD------LYTPLNPEE----RQLLRPGD 91
            |.:.||.:      |:.....|.   ..|.....:||:      :||.....|    .:|.:|..
Zfish    10 CFLMISQL------TDGATFQGNRADTEPEARMKMRYEPKSVFRVYTDGEYTEDTCALELFQPHT 68

  Fly    92 LTMLRNSHFNPKWPVRVSIHGWA-----GKSVTCSNAAIKDAYLSRGNYNVIILDWSRQSLDIS- 150
            |..   ..||...|:.:.||||:     .|.::...:|:|.   |.||.||:|.||    |.::
Zfish    69 LDA---CGFNSSLPLAIIIHGWSVDGMMEKWISRLASALKS---SEGNINVLIADW----LTLAH 123

  Fly   151 --YPRVSKQLPSIAANVAKMLRFLHDNTGVPYEQIYMIGHSAGSHISGLTGK--LLRPHRLGAIF 211
              ||..::....:..::|.:|.:|.|....|..::::||:|.|:||||..|.  .:....||.|.
Zfish   124 QHYPIAAQNTRIVGQDIAHLLSWLEDFKQFPLGKVHLIGYSLGAHISGFAGSNLAMSGRTLGRIT 188

  Fly   212 ALDPAGLTQLSLGPEERLDVNDALYVESIHT-DLTLLG---NPSTKLSHASFFANWGLGQPHCP- 271
            .|||||.....:...:||...||.:|::||| .|..:|   .....::|..|:.|.|..||.|.
Zfish   189 GLDPAGPMFEGMSHTDRLSPEDAKFVDAIHTFTLQRMGLSVGIKQPVAHFDFYPNGGSFQPGCQL 253

  Fly   272 ------------NATATEFDFVCDHFAAMFYFAES-VRQPKSFAALRCSSAKSVLSATC------ 317
                        .....|....|.|..|:..|.:| :.:.|...|.:||...:.....|
Zfish   254 HMQNIYAHLAQHGIMGFEQTVKCAHERAVHLFIDSLLNKDKQIMAYKCSDNTAFDKGNCLDCRKN 318

  Fly   318 NCNVGGSEKYAVNTCTGNEFMGGEPAVPKRGIFYLSTRPQSPY 360
            .||..|.:...|.|           ...||  .:|.||...||
Zfish   319 RCNTLGYDIKKVRT-----------GKSKR--LFLKTRSHMPY 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sxe2	NP_001287352.1	Lipase	53..360	CDD:278576	92/353 (26%)
sxe2	NP_001287352.1	Pancreat_lipase_like	72..356	CDD:238363	88/327 (27%)
lipca	NP_957316.1	lipo_lipase	44..488	CDD:132274	89/328 (27%)
		Pancreat_lipase_like	54..344	CDD:238363	84/312 (27%)
		PLAT_LPL	351..485	CDD:238856
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578613
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.840