DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sxe2 and Pnlip

DIOPT Version :9

Sequence 1:	NP_001287352.1	Gene:	sxe2 / 41954	FlyBaseID:	FBgn0038398	Length:	387	Species:	Drosophila melanogaster
Sequence 2:	NP_037293.2	Gene:	Pnlip / 25702	RGDID:	3360	Length:	465	Species:	Rattus norvegicus

Alignment Length:	394	Identity:	114/394 - (28%)
Similarity:	170/394 - (43%)	Gaps:	90/394 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LLWTCLLLLGA-AGTDASVDYFAYAPGKCEVSISDVIQGMITTEA---GVILGRP------RPSQ 67
            :|||..:|||| ||.:...|..                |..:.:|   |.| .||      .|:|
  Rat     3 MLWTFAVLLGAVAGKEVCFDKL----------------GCFSDDAPWSGTI-DRPLKALPWSPAQ 50

  Fly    68 TKLLRYDLYTPLNPEERQLLRPGDLTMLRNSHFNPKWPVRVSIHGWAGK------SVTCSNAAIK 126
            .. .|:.|||..|.:..|.: ..|.:.:|||:|......|:.|||:..|      |..|.|
  Rat    51 IN-TRFLLYTNENQDNYQKI-TSDASSIRNSNFKTNRKTRIIIHGFIDKGEENWLSDMCKN---- 109

  Fly   127 DAYLSRGNYNVIILDWSRQSLDISYPRVSKQLPSIAANVAKMLRFLHDNTGVPYEQIYMIGHSAG 191
              .....:.|.|.:||...| ..:|.:.::.:..:.|.||.::..|..:.|...:.:::||||.|
  Rat   110 --MFKVESVNCICVDWKGGS-RATYTQATQNVRVVGAEVALLVNVLKSDLGYSPDNVHLIGHSLG 171

  Fly   192 SHISGLTGKLLRPH-RLGAIFALDPA-----GLTQLSLGPEE-RLDVNDALYVESIHTD----LT 245
            ||::|..||  |.. .:|.|..||.|     |.      ||| |||..||.:|::||||    :.
  Rat   172 SHVAGEAGK--RTFGAIGRITGLDAAEPYFQGT------PEEVRLDPTDAQFVDAIHTDAAPIIP 228

  Fly   246 LLG-NPSTKLSHASFFANWGLGQPHCPNATATEF-----------DF-VCDHFAAMFYFAESVRQ 297
            .|| ..|..:.|..||.|.|:..|.|.....::.           || .|:|..:..|:.:|:..
  Rat   229 NLGFGMSQTVGHLDFFPNGGMEMPGCQKNILSQIVDIDGIWEGTRDFAACNHLRSYKYYTDSIVN 293

  Fly   298 PKSFAALRCSSAKSVLSATCNCNVGGSE------KYAVNTCTGNEFMGGEPAVPKRGIFYLSTRP 356
            |..|:...||| .:|.||. .|...|||      .||      :::.|....:.::  |||:|..
  Rat   294 PTGFSGFSCSS-YNVFSAN-KCFPCGSEGCPQMGHYA------DKYPGKTKELYQK--FYLNTGD 348

  Fly   357 QSPY 360
            :|.:
  Rat   349 KSNF 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sxe2	NP_001287352.1	Lipase	53..360	CDD:278576	103/351 (29%)
sxe2	NP_001287352.1	Pancreat_lipase_like	72..356	CDD:238363	95/319 (30%)
Pnlip	NP_037293.2	Lipase	17..352	CDD:395099	105/378 (28%)
Pnlip	NP_037293.2	PLAT_PL	355..465	CDD:238857
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339026
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.840