DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sxe2 and Pnliprp1

DIOPT Version :9

Sequence 1:	NP_001287352.1	Gene:	sxe2 / 41954	FlyBaseID:	FBgn0038398	Length:	387	Species:	Drosophila melanogaster
Sequence 2:	NP_061362.1	Gene:	Pnliprp1 / 18946	MGIID:	97723	Length:	473	Species:	Mus musculus

Alignment Length:	376	Identity:	109/376 - (28%)
Similarity:	158/376 - (42%)	Gaps:	65/376 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LLWTC-LLLLGAA-GTDASVDYFAYAPGKCEVSISDVIQGMITTEAGVILGRPRPSQTKLLRYDL 75
            :|||. |.||||| |.:...|...     | .|.::...|.......::...|....|:.|   |
Mouse     3 ILWTIPLFLLGAAQGKEVCYDNLG-----C-FSDAEPWAGTAIRPLKLLPWSPEKINTRFL---L 58

  Fly    76 YTPLNPEERQLLRPGDLTMLRNSHFNPKWPVRVSIHGWAGKSV------TCSNA-AIKDAYLSRG 133
            ||..||...|.|:..|.:.:..|:|......|..|||:..|..      .|.|. .:::.
Mouse    59 YTNENPTAFQTLQLSDPSTIEASNFQVARKTRFIIHGFIDKGEENWVVDMCKNMFQVEEV----- 118

  Fly   134 NYNVIILDWSRQSLDISYPRVSKQLPSIAANVAKMLRFLHDNTGVPYEQIYMIGHSAGSHISGLT 198
              |.|.:||.|.| ..:|.:.:..:..:.|.||:|:..|..|......::::||||.|:|::|..
Mouse   119 --NCICVDWKRGS-QTTYTQAANNVRVVGAQVAQMIDILVRNFNYSASKVHLIGHSLGAHVAGEA 180

  Fly   199 GKLLRPHRLGAIFALDPAGLTQLSLGPEERLDVNDALYVESIHTD----LTLLG-NPSTKLSHAS 258
            |.  |...||.|..|||..........|.|||.:||.:|:.||||    :..|| ..:..:.|..
Mouse   181 GS--RTPGLGRITGLDPVEANFEGTPEEVRLDPSDADFVDVIHTDAAPLIPFLGFGTNQMVGHFD 243

  Fly   259 FFANWGLGQPHCPNATATEF-----------DFV-CDHFAAMFYFAESVRQPKSFAALRCSSAKS 311
            ||.|.|...|.|.....::.           ||| |:|..:..|:.||:..|..|||..|:|.:.
Mouse   244 FFPNGGQYMPGCKKNALSQIVDIDGIWSGTRDFVACNHLRSYKYYLESILNPDGFAAYPCASYRD 308

  Fly   312 VLSATC------NCNVGG--SEKYAVNTCTGNEFMGGEPAVPKRGIFYLST 354
            ..|..|      .|...|  ::|:|.||..       ||..     |:|:|
Mouse   309 FESNKCFPCPDQGCPQMGHYADKFANNTSV-------EPQK-----FFLNT 347

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sxe2	NP_001287352.1	Lipase	53..360	CDD:278576	95/334 (28%)
sxe2	NP_001287352.1	Pancreat_lipase_like	72..356	CDD:238363	92/315 (29%)
Pnliprp1	NP_061362.1	Lipase	18..353	CDD:278576	99/361 (27%)
		Pancreat_lipase_like	52..349	CDD:238363	94/321 (29%)
		PLAT_PL	356..467	CDD:238857
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835408
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840