|
Fly 1 MAEDTEYKKLPVEERCVHKLWKARVDGYEEAAKIFRELDDEKSPEWSKFAGLIKKMVVDSNALAQ 65
|.:|:|:.||||:::|.|||||||:.|||||.|||:::.|||||||||:.|||||.|.||||:.|
Rat 1 MGDDSEWLKLPVDQKCEHKLWKARLSGYEEALKIFQKIKDEKSPEWSKYLGLIKKFVTDSNAVVQ 65
Fly 66 EKGLEAALIFVENSGLAGRTVGDVMTGIVQKCIAAPKTKTKELSVQVALMYVEIEKQEAVVEELV 130
.|||||||::|||:.:||:|.|:|::|:|.|....||.|.|||.:::.||||||||.|:|.|||:
Rat 66 LKGLEAALVYVENAHVAGKTTGEVVSGVVSKVFNQPKAKAKELGIEICLMYVEIEKGESVQEELL 130
Fly 131 KGMEAKNPKIVSACVAATTLALREFGHKVIGVKPLIKKLAPLMSDRDKTVRDEGKQLAVEIYRWI 195
||::.|||||:.||:.....||.|||.|:|.:||:||.|..|...|||.||||.|..|:|||||.
Rat 131 KGLDNKNPKIIVACIETLRKALSEFGSKIILLKPIIKVLPKLFESRDKAVRDEAKLFAIEIYRWN 195
Fly 196 GAAMKAQISTLPQVTLKELEDEFDKLKGERVEPSRYLKSQQEKQAKI--ADAAATEDAYNEDDGE 258
..|:|..:..:..|.|||||:|:.||.....:|||:|:||||.:||: ..:|..:.....|||:
Rat 196 RDAVKHTLQNINSVQLKELEEEWVKLPTGAPKPSRFLRSQQELEAKLEQQQSAGGDAEGGGDDGD 260
Fly 259 AGVEEIDPMDLLDPVDILSKMPKDFYDKLEEKKWTLRKESLEVLEKLLTDHPKLENGEYGALVSA 323
. |.:||..:||:.|:||||:|||||||:|.|||..|||:||.:|.|:.. |:||.|:|..||.|
Rat 261 E-VPQIDAYELLEAVEILSKLPKDFYDKIEAKKWQERKEALEAVEGLVRS-PRLEAGDYAELVKA 323
Fly 324 LKKVITKDSNVVLVAMAGKCLALLAKGLAKRFSNYASACVPSLLEKFKEKKPNVVTALREAIDAI 388
||||:.||:||:|||:|.|||..||.||.|:|..||...||::|||||||||.||.||:||||||
Rat 324 LKKVVGKDTNVMLVALAAKCLTGLAVGLRKKFGQYAGHVVPTILEKFKEKKPQVVQALQEAIDAI 388
Fly 389 YASTSLEAQQESIVESLSNKNPSVKSETALFIARALTRTQPTALNKKLLKLLTTSLVKTLNEPDP 453
:.:|:|:...|.::..:.||||::|.:|:|||||:......:.|.|.|||....:|:|.:|:..|
Rat 389 FLTTTLQNISEDVLAVMDNKNPTIKQQTSLFIARSFRHCTSSTLPKSLLKPFCAALLKHINDSAP 453
Fly 454 TVRDSSAEALGTLIKLMGDKAVTPLLADVDPLKMAKIKECQEKAEI----KIKVAGPKKETRPAS 514
.|||::.|||||.:|::|:|.|.|.|||||.||:.|||||.||.|: |..:|..|||::|..
Rat 454 EVRDAAFEALGTALKVVGEKTVNPFLADVDKLKLDKIKECSEKVELVHGKKSGLAAEKKESKPLP 518
Fly 515 APTAKAAAPAKTVAGSVDPKPVTRPATTGARKVLKKPATVSGG----GATSAPTAALKAG---GK 572
...|.:.| ||..|.|.|:.| ..|..| |.|||.:|| |.|:||..:..:| .|
Rat 519 GRAAASGA-----AGDKDTKDVSGP-KPGPLK--KAPATKAGGPPKKGKTTAPGGSASSGTKNKK 575
Fly 573 PLAT----EREITPEELQEKSEEILPAEILNGLVDSNWKNRLAAVEQLLGEISGFDAKQAGISQI 633
.|.| |.|::.|..:||:..:||...:..|..||||.|||.:|:....:...:..:.. .|.
Rat 576 GLETKEIAEPELSIEVCEEKASAVLPPTCIQLLDSSNWKERLACMEEFQKAVELMERSEMP-CQA 639
Fly 634 LIRTISGRKPGLKEMNFQVLKFKLDIIRSVAENYPLTTTTVDLVINEIIEKLADAKNGAAAADVL 698
|::.:: :|||.||.||||::.||.|:..:|:....:.|:..:|::.:::|:.|.|.|..|.:.|
Rat 640 LVKMLA-KKPGWKETNFQVMQMKLHIVALIAQKGNFSKTSAQIVLDGLVDKIGDVKCGNNAKEAL 703
Fly 699 SAFAEATKLEYVVGKVLSFAFEQKSPKVQSEAFNWVNRSIIEFGF-QLQPKTLIEDVRKGVQSTN 762
:|.|||..|.:...:|:|.||.||:||.|||..||::.:|.|||| :|..|..|.:|:..:.:||
Rat 704 TAIAEACMLPWTAEQVMSMAFSQKNPKNQSETLNWLSNAIKEFGFSELNVKAFISNVKTALAATN 768
Fly 763 PTVRASAIQMVGTMSMYMGKALMMFFDSEKPALKSQIQVEFDKNVGEKPPKPVRGVQRSSGGTAG 827
|.||.|||.::|.|.:|:|.:|.|.|:.|||||.|||..||.|..|:.||.|.||:.:.| |:|
Rat 769 PAVRTSAITLLGVMYLYVGPSLRMIFEDEKPALLSQIDAEFQKMQGQSPPAPTRGISKHS--TSG 831
Fly 828 NSPDNEDDDGGAAGEEEPINMADLLPRVDIAPQITEALLKEMSDKDWKTRNEGLTKLQAIISEAR 892
. :|.|||...|:... ::.||||||:|:.:||..|:.::.||:||.|.|||.::..||:||:
Rat 832 T---DEGDDGDEPGDGSN-DVVDLLPRVEISDKITSELVSKIGDKNWKIRKEGLDEVAGIINEAK 892
Fly 893 LIKPSIGDLAPALAHRLVDSNAKIAQTTLAICEQLATAMGAGCRNHVRNLFPGFLHALGDNKSFV 957
.|:|:||:|..||..||.|||..:.|.||.|.:|||.|||...:.||:||....|..|||:|:.|
Rat 893 FIQPNIGELPTALKGRLNDSNKILVQQTLNILQQLAVAMGPNVKQHVKNLGIPILTVLGDSKNNV 957
Fly 958 RAAALNCINSFGEKGGYKEFFESEMIADALKGGSPALKTELWAWLADKLPGLPPKSVSKEDIHSM 1022
|||||..:|::.|:.|.||:.|.|.:::.||..:|.|:.||..|||:|||.| ..:..|:...
Rat 958 RAAALATVNAWAEQTGMKEWLEGEDLSEELKKENPFLRQELLGWLAEKLPML---RSTPTDLILC 1019
Fly 1023 VPHLYAHICDRNADVRKNANEAVLGIMIHLGFDAMNRALDKQKPASKKDILAALEKARPNLPVKP 1087
|||||:.:.|||.||||.|.:|:...|:|||::.|.:|..|.||.||..:||.||||:.|:|.||
Rat 1020 VPHLYSCLEDRNGDVRKKAQDALPFFMMHLGYEKMAKATGKLKPTSKDQVLAMLEKAKANMPSKP 1084
Fly 1088 L--------PKG-----KHQ---API-----------PEEPKLKTVRGGGAGGAPGIQKSATARV 1125
. |.| |.| ||: |:..|.| |||:...|.:
Rat 1085 AAPSKAVSKPMGGSAPAKTQPIPAPVEDSVSNTMEAKPDPKKAK---------APGVSSKAKS-- 1138
Fly 1126 AGGQDKQVPAR---KKDEDIDTSPLLCANSAKNQRLLDEQKMKVLKWTFVTPREEFTELLRDQMM 1187
.|.|:||:: |:|:|......:...:.|.||:.||:.:|||||.|.|||:|:.|.|:.||.
Rat 1139 --AQGKKVPSKTTLKEDDDKSGPIFIVVPNGKEQRMRDEKGLKVLKWNFTTPRDEYIEQLKTQMS 1201
Fly 1188 TANVNKALIANMFHDDFRYHLKVIEQLSEDLAGNSKALVCNLDLILKWLTLRFYDTNPSVLIKGL 1252
:. |.|.|...|||.||::|.|.:..:.:.|......::..||||||||||||:|||.|||:|.|
Rat 1202 SC-VAKWLQDEMFHADFQHHNKALAVMVDHLESEKDGVISCLDLILKWLTLRFFDTNTSVLMKAL 1265
Fly 1253 EYLVQVFQVLIDEEYILAENEGSSFVPHLLLKIGDPKDAVRNGVRRVLRQVILVFPFVKVFGYVM 1317
|||..:|.:|.||||.|.|||.|||:|:|:||:|:|||.:|..||.:|.::.||:|..|:|.::|
Rat 1266 EYLKLLFTLLSDEEYHLTENEASSFIPYLILKVGEPKDVIRKDVRAILNRMCLVYPASKMFPFIM 1330
Fly 1318 EGLKSKNARQRTECLDELTFLIESYGMNIC---PQSAVREIARQISDRDNSVRNAALNCIVQVFF 1379
||.||||::||.|||:||..||||||||:| |..|::|||..|.||||:|||||||.||.|:.
Rat 1331 EGTKSKNSKQRAECLEELGCLIESYGMNVCQPTPGKALKEIAIHIGDRDNAVRNAALNTIVTVYN 1395
Fly 1380 LSGEKTYKMIGHLNEKDLSMLDERIKRAKKTKKPTPPPSVDVPAPQRHDSIEIEDAEVGNGCDEL 1444
:.|::.:|:||:|:|||:|||:|||||:.| |..::.::.|| |.
Rat 1396 VHGDQVFKLIGNLSEKDMSMLEERIKRSAK----------------RPSAVPVKQAE------EK 1438
Fly 1445 PPPDEDGLQRELNARGQNNMTDRSATNVVAYLSSLTRQATFDQAPSSQLLLLQQQLQQLQQQAQQ 1509
| ||..|.....||..:.... ..|..|.:..:..::|.::..
Rat 1439 P-------QRTQNINSNANMLRKGPAE-----------------DMSSKLKIMYRTYRIQARSMS 1479
Fly 1510 QKPSG------PFGLDSQVISEIEKD--WVRVDQMEQKPLLNVDISSLDEPIKVRPTRAGIHYPQ 1566
..|.. .|.|| :.|||.| .||.:..| |:...:..:.||:.: |:
Rat 1480 GHPEAAQMVRREFQLD---LDEIENDNGTVRCEMPE---LVQHKLDDIFEPVLI---------PE 1529
Fly 1567 EKFDRLISRQHYMQQTLTTSPSSTAGMTSGVSPYRSPMRLQHQQPQQQLENNIPNLADVLPKHDP 1631
.|. ..|||:...|. .|.|..:.
Rat 1530 PKI-------------------------RAVSPHFDDMH--------------SNTASTIN---- 1551
Fly 1632 QLVKVIKGVSSTDTLKARAAINELAAIIEAPEKQAVLRDYEEIFIQNVLAQFKNLSQIPSA---- 1692
.:|..|:|.|...:..|:.::..::...:|...:..:.:.|: :|.|..|..|.|.
Rat 1552 ---FIISQVASGDISTSIQALTQIDEVLRQEDKAEAMSGHIDQFL---IATFMQLRLIYSTHMAD 1610
Fly 1693 ------QSVVVYQPLLSILYTFFHANILGKTLSVACIKNLMSALLNLMADPKLA-VGDDSQYNKV 1750
:.:.:|..::..:.:.|....|.:..|...:|:||..|:.||.|.::. :.:..|..:.
Rat 1611 EKLDKDEIIKLYSCIIGNMISLFQIESLAREASTGVLKDLMHGLITLMLDSRIEDLEEGQQVIRS 1675
Fly 1751 INGICLKVLDKVDFTNLNCALIRLLRET-CPEAKLPKFTDLLMKCIWRNVKMLPERSNELNYDAV 1814
:|.:.:|||:|.|.||:..||:.||::: ...|..|||::|:|||:||.|::||:..|.:|.|.:
Rat 1676 VNLLVVKVLEKSDQTNILSALLVLLQDSLLATASSPKFSELVMKCLWRMVRLLPDTINSINLDRI 1740
Fly 1815 ILEVHEFMLALPSTWWQNRPSDTPMRTIKTILHNMAKVKGNAILQHLNQI--PTHSELHTYLIRI 1877
:|::|.||...|....:...|:.|:||:||:||.:.|:||..||.||..| ...|||..:|.|:
Rat 1741 LLDIHIFMKVFPKEKLKQCKSEFPIRTLKTLLHTLCKLKGPKILDHLTMIDNKNESELEAHLCRM 1805
Fly 1878 LKNFQKDGSASGIGASPQRAKEIASKRISHQTHDTVSQIFKLISDRDTKQQGLQKLYDFKQQNPD 1942
:|:......:.....:.:.|..|..|....:.:|.:::|||.|..::..::||.:||::|::..|
Rat 1806 MKHSMDQTGSKSDKETEKGASRIDEKSSKAKVNDFLAEIFKKIGSKENTKEGLAELYEYKKKYSD 1870
Fly 1943 IDLSTFLQGSSAPFHKYIEEGLAEIERNQ--------NAG-STQDNRT-----AATRSYLTDVNY 1993
.|:..||:.||..|..|:|.||..||..: :|| |.|...| .:|.|.|.:.|.
Rat 1871 TDIEPFLKNSSQFFQSYVERGLRVIEMERESKGRIPTSAGISPQMEVTCVPTPTSTVSSLGNTNG 1935
Fly 1994 QNNGPDPDFWMDRLQYHMTGGAAKLASARSADDGSHMLDNKVVDENLCLNGMNAQKASLIKREKR 2058
:..| |..:::|| |:...|.. |||...|:...|..:.::.|........
Rat 1936 EEVG--PSVYLERL---------KILRQRCG------LDNTKQDDRPPLTSLLSKPAIPPVASST 1983
Fly 2059 DMSPNRLQHLQAKLAQIK--KENH 2080
|| |.:||:|:: :|.|
Rat 1984 DM-------LHSKLSQLRESREQH 2000
| 
