DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment GATAe and gata3

DIOPT Version :9

Sequence 1:	NP_650516.2	Gene:	GATAe / 41945	FlyBaseID:	FBgn0038391	Length:	746	Species:	Drosophila melanogaster
Sequence 2:	NP_001004967.1	Gene:	gata3 / 448391	XenbaseID:	XB-GENE-485930	Length:	437	Species:	Xenopus tropicalis

Alignment Length:	508	Identity:	127/508 - (25%)
Similarity:	182/508 - (35%)	Gaps:	190/508 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   277 QHQQQHH---------------------------QHQAAAAASAAAQTVHIATSSHGGTVRFVT- 313
            ||...||                           .|..:..:::...........||..|...:
Frog    23 QHSDSHHPVHNYIDPTQYPPPEDMDVLFNIDGQGNHVPSYYSNSVRTVPRYPPPHHGSLVCHPSI 87

  Fly   314 ----EDVRFTTAGPETSASNMYYDVPVVDGSVHANESKTYADLGNAYAPFPPSSSFSSNSYAATL 374
                .|.|.:..||..:::   :::|....|:|.|..       ...:.:||:||       |:|
Frog    88 LQSWTDGRKSLGGPHAASA---WNLPFAKPSIHHNSP-------GGLSVYPPASS-------ASL 135

  Fly   375 QQGNT---IYSVPGTGQFLAKSESGLNQTGLLRQTGPATFQTISFEGGNGIEPLWASPAPPEYQS 436
            ..|::   :::.|.|                                    .|...||.|....|
Frog   136 ATGHSSPHLFTFPPT------------------------------------PPKDVSPDPSISTS 164

  Fly   437 VQFSNFHPQ----VIDEY---------------------GSGNMSTSHWPPASSIGQY------D 470
            |..|:...:    |:.:|                     |.|.:|::|.|..:....|      .
Frog   165 VSTSSSRHEEKECVVSKYQVSLSEPGMKLESSHPRNSMSGIGGVSSAHHPITTYPDYYGAGLFQP 229

  Fly   471 GSLVTASSTSSPN----------HELKCENCHG---PFLRKG--SEYFCPNCPAFMRM----APR 516
            ||::..|.|..|:          ...:|.||..   |..|:.  ..|.|..|..:.:|    .|.
Frog   230 GSILDGSPTHFPSKPRPKTRSSTEGRECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPL 294

  Fly   517 ITQRQAKPK--AAAAPNNRRNGVTCANCQTNSTTLWRRNNEGNPVCNACGLYYKLHNMNRPLSMK 579
            |     |||  .:||   ||.|.:||||||.:|||||||..|:||||||||||||||:||||:||
Frog   295 I-----KPKRRLSAA---RRAGTSCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNINRPLTMK 351

  Fly   580 KEGIQKRKRK--PKNNGGAPMHRAPLPSMSQGVNLMANSPLYPSQVPVSMLNSQLNSQQNSSPEL 642
            |||||.|.||  .|:.....:|           :.:.:.|...|..|.: |:..::|..:.||..
Frog   352 KEGIQTRNRKMSSKSKKSKKIH-----------DSLEDYPKSSSFSPAA-LSRHMSSLSHISPFS 404

  Fly   643 HD--MSTTGQAGGQRVVSISLNATAPPTPDGTLNMSARHHVTGESHSPYSQQS 693
            |.  |.||                  |||        .|..:|.|..|:...|
Frog   405 HSSHMLTT------------------PTP--------MHAPSGLSFGPHHPSS 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GATAe	NP_650516.2	ZnF_GATA	534..583	CDD:214648	38/48 (79%)
GATAe	NP_650516.2	ZnF_GATA	538..589	CDD:238123	40/50 (80%)
gata3	NP_001004967.1	ZnF_GATA	256..306	CDD:238123	16/57 (28%)
gata3	NP_001004967.1	ZnF_GATA	310..360	CDD:238123	40/49 (82%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000130
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000