DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GATAe and gata5

DIOPT Version :9

Sequence 1:	NP_650516.2	Gene:	GATAe / 41945	FlyBaseID:	FBgn0038391	Length:	746	Species:	Drosophila melanogaster
Sequence 2:	NP_571310.2	Gene:	gata5 / 30482	ZFINID:	ZDB-GENE-980526-340	Length:	383	Species:	Danio rerio

Alignment Length:	429	Identity:	122/429 - (28%)
Similarity:	166/429 - (38%)	Gaps:	129/429 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   340 SVHANESKTYADLGNAYAPFPPSSSFSSNSYAATLQQGNTIYSVPGTGQFLAKSES-----GLNQ 399
            ::.:|.|....|.||...|     |.||..|..|.:....:.::|    :|...||     |::.
Zfish     6 ALSSNPSPYAHDSGNYIHP-----SASSPVYVPTTRVPAMLQTLP----YLQTCESSHQAHGISS 61

  Fly   400 TGLLRQTGPATFQTISFEGGNGIEPLWASPAPPEYQSVQFSNFH-PQV----------------- 446
            .....|||.   ...||..|        ||.||.    .||..| |.|
Zfish    62 HHAWPQTGT---DNSSFNPG--------SPHPPP----GFSYSHSPPVSSSTGRDAAYQNPLMLS 111

  Fly   447 ----IDEYGSG-------------------NMSTSHWPPASSIGQYDGSLVTASSTSS------- 481
                .|:|||.                   .|:|| |.|    |.:||.::.......
Zfish   112 NGGRADQYGSALVRSVGGSYSSPYAAYMSPEMATS-WTP----GPFDGGMIGLQGRQGTLPGRRS 171

  Fly   482 --------PNHELKCENCHG---PFLRKG--SEYFCPNCPAFMRMAPRITQRQAKPKAAAAPNNR 533
                    |....:|.||..   |..|:.  ..|.|..|..:.:| ..|.:...||:......:|
Zfish   172 SIDMLDDLPCEGRECVNCGSISTPLWRRDGTGHYLCNACGLYHKM-NGINRPLIKPQKRLQSTSR 235

  Fly   534 RNGVTCANCQTNSTTLWRRNNEGNPVCNACGLYYKLHNMNRPLSMKKEGIQKRKRKPKNNGGAPM 598
            |.|:.|.||.|::|||||||.||.|||||||||.|||.:.|||:||||.||.||||||
Zfish   236 RAGLCCTNCHTSTTTLWRRNAEGEPVCNACGLYMKLHGVPRPLAMKKESIQTRKRKPK------- 293

  Fly   599 HRAPLPSMSQGVNLMANSPLYPSQVPVSMLNSQLNSQQN--SSPELHDMSTTGQAGGQRVVSISL 661
                :|..........:....|:.:|||...|.:.|:.:  :||          ..||.|||::.
Zfish   294 ----MPKTKSSSGSTVSGATSPTSLPVSENASTIKSEPSIAASP----------YAGQTVVSVTQ 344

  Fly   662 NATAPPTPDGTLNMSARHHVTGESHSPYSQQSTPQSQSP 700
            .:|       .|:.::..|| ...:..|:.  ||.|.:|
Zfish   345 AST-------QLDSASSAHV-DIKYEDYTY--TPTSIAP 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GATAe	NP_650516.2	ZnF_GATA	534..583	CDD:214648	34/48 (71%)
GATAe	NP_650516.2	ZnF_GATA	538..589	CDD:238123	36/50 (72%)
gata5	NP_571310.2	GATA-N	1..173	CDD:283099	43/195 (22%)
		ZnF_GATA	182..228	CDD:214648	12/46 (26%)
		ZnF_GATA	185..236	CDD:238123	12/51 (24%)
		ZnF_GATA	236..285	CDD:214648	34/48 (71%)
		ZnF_GATA	241..291	CDD:238123	36/49 (73%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5641
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000130
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	4	3.770