Protein Alignment GATAe and GATA2

DIOPT Version :9

• Sequence 1: NP_650516.2
• Gene: GATAe / 41945
• FlyBaseID: FBgn0038391
• Length: 746
• Species: Drosophila melanogaster
• Sequence 2: NP_001139133.1
• Gene: GATA2 / 2624
• HGNCID: 4171
• Length: 480
• Species: Homo sapiens
• Alignment Length: 412
• Identity: 119/412 - (28%)
• Similarity: 161/412 - (39%)
• Gaps: 108/412 - (26%)

  Fly   282 HHQ------------HQAAAAASAAAQTVHIATSSHGGTVRFVTEDVRFTTAGPETSASNMYYDV 334
            ||.            |.:||.......:|:  ..:.||:.......|...|.....|.|:::...
Human   112 HHNPWTVSPFSKTPLHPSAAGGPGGPLSVY--PGAGGGSGGGSGSSVASLTPTAAHSGSHLFGFP 174

  Fly   335 PVVDGSVHANESKTYADLGNAYAPFPPSSSFSSNSYAATLQQGNTIYSVPGTGQFLAKSESGLNQ 399
            |.....|..:.|.|.|        ..|:||.:..|.|....:....|.|       :.:||...:
Human   175 PTPPKEVSPDPSTTGA--------ASPASSSAGGSAARGEDKDGVKYQV-------SLTESMKME 224

  Fly   400 TGLLRQTGPATFQTISFEGGNGIEPLWASPAPPEYQSVQFSNFHPQVIDEYGSGNMSTSHW--PP 462
            :|...:.|.||.         |.:|....|.|      .:.::.|....:|.||......:  .|
Human   225 SGSPLRPGLATM---------GTQPATHHPIP------TYPSYVPAAAHDYSSGLFHPGGFLGGP 274

  Fly   463 ASSIGQYDGSLVTASSTSSPNHELKCENCHG---PFLRKG--SEYFCPNCPAFMRM----APRIT 518
            |||......|...:.|...     :|.||..   |..|:.  ..|.|..|..:.:|    .|.|
Human   275 ASSFTPKQRSKARSCSEGR-----ECVNCGATATPLWRRDGTGHYLCNACGLYHKMNGQNRPLI- 333

  Fly   519 QRQAKPK--AAAAPNNRRNGVTCANCQTNSTTLWRRNNEGNPVCNACGLYYKLHNMNRPLSMKKE 581
                |||  .:||   ||.|..||||||.:|||||||..|:||||||||||||||:||||:||||
Human   334 ----KPKRRLSAA---RRAGTCCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNVNRPLTMKKE 391

  Fly   582 GIQKRKRKPKNNG--------------------GAPM-------HRAP---LPSMSQGVNLMAN- 615
            |||.|.||..|..                    .:|.       |.||   ||..|...:::..
Human   392 GIQTRNRKMSNKSKKSKKGAECFEELSKCMQEKSSPFSAAALAGHMAPVGHLPPFSHSGHILPTP 456

  Fly   616 SPLYPSQV-------PVSMLNS 630
            :|::||..       |.||:.:
Human   457 TPIHPSSSLSFGHPHPSSMVTA 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GATAe	NP_650516.2	ZnF_GATA	534..583	CDD:214648	38/48 (79%)
		ZnF_GATA	538..589	CDD:238123	40/50 (80%)
GATA2	NP_001139133.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	119..209		20/99 (20%)
		ZnF_GATA	294..344	CDD:238123	16/57 (28%)
		ZnF_GATA	349..398	CDD:238123	40/48 (83%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	448..480		6/31 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5641
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000130
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10071
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.910