DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment GATAe and SPCC1393.08

DIOPT Version :9

Sequence 1:	NP_650516.2	Gene:	GATAe / 41945	FlyBaseID:	FBgn0038391	Length:	746	Species:	Drosophila melanogaster
Sequence 2:	NP_587966.1	Gene:	SPCC1393.08 / 2538884	PomBaseID:	SPCC1393.08	Length:	557	Species:	Schizosaccharomyces pombe

Alignment Length:	591	Identity:	127/591 - (21%)
Similarity:	195/591 - (32%)	Gaps:	163/591 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   128 LELNEARE-----GEPSTNASNASSGSASDSHIEYQRSAHQSPGATHYVQMAPRNAEVTEQVGAA 187
            :..|:..|     |:||...|..:.||......|:. ....||..|....:|  |..:.....|.
pombe     1 MNYNDTTEFCFPFGQPSFPTSAMTEGSFDGQFSEFD-PTFTSPADTALSDIA--NLPIDLHKDAL 62

  Fly   188 AGAPPGTIFAYPIICNGD-DVAAIK-IETLEKGEATGESQQQQQQLQQH-----------QHQQQ 239
            ....||         .|| |..::. ::.|........|.:..|:||.:           ....|
pombe    63 FANAPG---------KGDVDFDSVSMLQLLSDYPLAFNSTENNQKLQTNPSARWSLLDSMDFDNQ 118

  Fly   240 QQCPTPNGASYGETIVISSEAEALQHHHQQQQQHQQQQHQQQHHQHQAAAAASAA---------- 294
            :||.....|..|::.::.|...:                    :.|...||.|::
pombe   119 RQCSDLESAQLGDSGLLKSTILS--------------------NSHIDIAALSSSKTSEPTPPFS 163

  Fly   295 -AQTVHIATSSHGGTVRFVTEDVRFTTAGPETSASNMYYD------VPVVDGSVH---------- 342
             .||..|.|.|          .....|..|....|...:|      .|..||...
pombe   164 YVQTPCIPTPS----------SALIDTPFPGALDSEFGFDESQAPLFPASDGDCQRAFASISYPT 218

  Fly   343 ------------ANESKTYADLGNAYAPFPPSSSFSS--NSYAATLQQGNTIYSVPGTGQFLAKS 393
                        :.:|....:|.::.:|...|.|.||  .|.:|.|.|...:.|||.....:|
pombe   219 NYGCKLSNLGFMSPQSPVKRELNDSTSPSKLSESSSSLTGSSSALLSQSEFLGSVPSLSDSIA-- 281

  Fly   394 ESGLNQTGLLRQTGPATFQTISFEGGNGIEPLW--ASPAPPEYQSVQFSNFHPQVIDEYGSGNMS 456
                        |....|...|||.......|.  ||...|::.:...|:         .|.::|
pombe   282 ------------TVDPFFSFESFETDEKARSLLMDASLKLPQFSTPNLSS---------NSSSLS 325

  Fly   457 TSHW--------PPASSIGQYDGSLVTASSTSSPNHELKCENC---HGPFLRKGSE---YFCPNC 507
            ....        .|.:::.....|..........:.|..|.||   ..|..|:.|:   :.|..|
pombe   326 LKSTLAEGMKGSTPLAAVKTEKASKAARVMKQKKHREHVCFNCGVTETPLWRRTSDKLNFLCNAC 390

  Fly   508 PAFMR----MAPRITQRQAKPKAAAAPNNRRNGVTCANCQTNSTTLWRRNNEGNPVCNACGLYYK 568
            ..:.:    |.|...:.:...||.       ..:.||||.:..|:|||::..|..||||||||.:
pombe   391 GLYNKQYGVMRPLSPRNKGSSKAL-------ENLVCANCSSTKTSLWRKDRHGQTVCNACGLYAR 448

  Fly   569 LHNMNRPLSMKKEGIQKRKRKPKNNGG----APMHRAPLPSMSQGVNLM-------ANSPLYPSQ 622
            ||..|||:.:||..| .|:|:.|..||    :...::..|.:|:.|.:.       ..||...:.
pombe   449 LHGHNRPIGLKKNKI-TRRRRGKGPGGEDGMSDEVKSEFPVLSKSVTMAEILSSKGLESPQLTNS 512

  Fly   623 VPVSML 628
            |.||.:
pombe   513 VSVSKM 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GATAe	NP_650516.2	ZnF_GATA	534..583	CDD:214648	24/48 (50%)
GATAe	NP_650516.2	ZnF_GATA	538..589	CDD:238123	26/50 (52%)
SPCC1393.08	NP_587966.1	GAT1	31..557	CDD:227928	119/561 (21%)
		ZnF_GATA	364..413	CDD:238123	10/48 (21%)
		ZnF_GATA	418..462	CDD:238123	24/43 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5641
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000130
OrthoInspector	1	1.000	-	-		otm47054
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10071
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.870