Protein Alignment GATAe and Gata3

DIOPT Version :9

• Sequence 1: NP_650516.2
• Gene: GATAe / 41945
• FlyBaseID: FBgn0038391
• Length: 746
• Species: Drosophila melanogaster
• Sequence 2: NP_032117.1
• Gene: Gata3 / 14462
• MGIID: 95663
• Length: 443
• Species: Mus musculus
• Alignment Length: 520
• Identity: 139/520 - (26%)
• Similarity: 195/520 - (37%)
• Gaps: 166/520 - (31%)

  Fly   255 VISSEAEALQHHHQQ--QQQHQQQQHQQQHHQHQAA---------AAASAAAQTVHIATSSHGGT 308
            |.:.:...:.|||..  ..||....|....|.:..|         ...:...|..|: .|.:|.:
Mouse     3 VTADQPRWVSHHHPAVLNGQHPDTHHPGLGHSYMEAQYPLTEEVDVLFNIDGQGNHV-PSYYGNS 66

  Fly   309 VRFVTEDVRFTTAGPETSASNMYYDVPVVDGSVHANESKTYADLGNAYAPFPPSSSFSSNSYAAT 373
            ||...:  |:    |.|...:.....|::.||:      .:.|.|.|.:....:|.::.:.::.|
Mouse    67 VRATVQ--RY----PPTHHGSQVCRPPLLHGSL------PWLDGGKALSSHHTASPWNLSPFSKT 119

  Fly   374 -LQQGN----TIYSVPGTGQFLAKSESGLNQTGLLRQTGPATFQTISFEGGNGIEPLWASPAPP- 432
             :..|:    ::|. |.:...||...|..:..     |.|.|            .|...||.|.
Mouse   120 SIHHGSPGPLSVYP-PASSSSLAAGHSSPHLF-----TFPPT------------PPKDVSPDPSL 166

  Fly   433 -----------------EYQ-----SVQFSNFH----------------------PQVIDEYGSG 453
                             :||     |::....|                      |..:.||.||
Mouse   167 STPGSAGSARQDEKECLKYQVQLPDSMKLETSHSRGSMTTLGGASSSAHHPITTYPPYVPEYSSG 231

  Fly   454 NMSTSHWPPASSIGQYDGSLVTASSTSSP-----NHELKCENCHG---PFLRKG--SEYFCPNCP 508
                 .:||:|.:|   ||.......|.|     ....:|.||..   |..|:.  ..|.|..|.
Mouse   232 -----LFPPSSLLG---GSPTGFGCKSRPKARSSTEGRECVNCGATSTPLWRRDGTGHYLCNACG 288

  Fly   509 AFMRM----APRITQRQAKPK--AAAAPNNRRNGVTCANCQTNSTTLWRRNNEGNPVCNACGLYY 567
            .:.:|    .|.|     |||  .:||   ||.|.:||||||.:|||||||..|:||||||||||
Mouse   289 LYHKMNGQNRPLI-----KPKRRLSAA---RRAGTSCANCQTTTTTLWRRNANGDPVCNACGLYY 345

  Fly   568 KLHNMNRPLSMKKEGIQKRKRK--PKNNGGAPMHRAPLPSMSQGVNLMANSPLYPSQVPVSMLNS 630
            ||||:||||:|||||||.|.||  .|:.....:|.|           :.:.|...|..|.: |:.
Mouse   346 KLHNINRPLTMKKEGIQTRNRKMSSKSKKCKKVHDA-----------LEDFPKSSSFNPAA-LSR 398

  Fly   631 QLNSQQNSSPELHD--MSTTGQAGGQRVVSISLNATAPPTPDGTLNMSARHHVTGESHSPYSQQS 693
            .::|..:.||..|.  |.||                  |||        .|..:|.|..|:...|
Mouse   399 HMSSLSHISPFSHSSHMLTT------------------PTP--------MHPPSGLSFGPHHPSS 437

  Fly   694  693
            Mouse   438  437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GATAe	NP_650516.2	ZnF_GATA	534..583	CDD:214648	38/48 (79%)
		ZnF_GATA	538..589	CDD:238123	40/50 (80%)
Gata3	NP_032117.1	Interaction with TBX21. /evidence=ECO:0000269|PubMed:15662016	1..257		56/292 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..28		6/24 (25%)
		PHA03377	<76..260	CDD:177614	39/215 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	143..180		8/53 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	193..214		1/20 (5%)
		ZnF_GATA	262..312	CDD:238123	16/57 (28%)
		Flexible linker. /evidence=ECO:0000250	288..316		11/35 (31%)
		ZnF_GATA	316..366	CDD:238123	40/49 (82%)
		YxKxHxxxRP	344..353		7/8 (88%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	412..443		11/52 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5641
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000130
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10071
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910