DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment GATAe and gata1

DIOPT Version :9

Sequence 1:	NP_650516.2	Gene:	GATAe / 41945	FlyBaseID:	FBgn0038391	Length:	746	Species:	Drosophila melanogaster
Sequence 2:	XP_031747036.1	Gene:	gata1 / 100497467	XenbaseID:	XB-GENE-484636	Length:	363	Species:	Xenopus tropicalis

Alignment Length:	322	Identity:	93/322 - (28%)
Similarity:	135/322 - (41%)	Gaps:	66/322 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   361 PSSSFSSNSYAATLQQGNTIYSVPGT-------GQFLAKSESGLNQTGLLRQTGPATFQTIS--- 415
            |..:::.::.|:|.:....:|.:.|.       |...:::..|...:.:| ||.|..:...|
Frog    11 PLPNYTESALASTSEDSEFLYGLGGESSPGHYGGTVSSRAVGGFRHSPVL-QTFPLHWPETSVGI 74

  Fly   416 ------FEGGNGIEPLWASPA--------PPEYQSVQFSNFHPQVIDEYGS----GNMSTSHWPP 462
                  :....|..||:.|.|        ||.|.:..|........:..||    ..:.|....|
Frog    75 PHSLTAYGRSPGTVPLYPSAASSFGPITSPPLYNAAPFLLGSAPPAEHEGSPKFLETLKTERTSP 139

  Fly   463 -----------ASSIGQYDGSLVTASSTSSPN-----HELKCENCHG---PFLRK--GSEYFCPN 506
                       :.|:.|. |.|.......||:     .:.:|.||..   |..|:  ...|.|..
Frog   140 LTTDLLPLESRSPSLPQV-GYLGVGGQEFSPSLFQSTEDRECVNCGATVTPLWRRDLSGHYLCNA 203

  Fly   507 CPAFMRM----APRITQRQAKPKAAAAPNNRRNGVTCANCQTNSTTLWRRNNEGNPVCNACGLYY 567
            |..:.:|    .|.|     :||..... ::|.|..|:||.|::|||||||..|:||||||||||
Frog   204 CGLYHKMNGQNRPLI-----RPKKRLIV-SKRAGTQCSNCHTSTTTLWRRNASGDPVCNACGLYY 262

  Fly   568 KLHNMNRPLSMKKEGIQKRKRKPKNNGGAPMH-RAPLPSMSQGVNLMANSP----LYPSQVP 624
            ||||:||||:|||||||.|.||..:....... ..|...:..||...:..|    |:..|:|
Frog   263 KLHNVNRPLTMKKEGIQTRNRKVSSKSKKKKQLDNPFEPLKAGVEEPSPYPFGPLLFHGQMP 324

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GATAe	NP_650516.2	ZnF_GATA	534..583	CDD:214648	36/48 (75%)
GATAe	NP_650516.2	ZnF_GATA	538..589	CDD:238123	38/50 (76%)
gata1	XP_031747036.1	GAT1	<70..283	CDD:227928	73/219 (33%)
		ZnF_GATA	179..223	CDD:238123	13/48 (27%)
		ZnF_GATA	233..283	CDD:238123	38/49 (78%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000130
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10071
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010