DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GATAe and trps1

DIOPT Version :9

Sequence 1:	NP_650516.2	Gene:	GATAe / 41945	FlyBaseID:	FBgn0038391	Length:	746	Species:	Drosophila melanogaster
Sequence 2:	XP_004915118.1	Gene:	trps1 / 100493561	XenbaseID:	XB-GENE-1013667	Length:	1270	Species:	Xenopus tropicalis

Alignment Length:	609	Identity:	139/609 - (22%)
Similarity:	211/609 - (34%)	Gaps:	187/609 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   198 YPIICNGDDVA--AIKIETLEKGEATGESQQQQQQLQQHQHQQQQQCPTPNGASYGETIVISSEA 260
            ||..|...:.:  |:.:..|..| .||.::.:         .|..||      |:.     |.:.
Frog   572 YPFACKKSNCSHCALLLLHLSAG-VTGSTRVK---------HQCDQC------SFS-----SPDV 615

  Fly   261 EALQHHHQQQQQHQQ-QQHQQQHHQHQAAAAASAAAQTVHIAT------------SSHGGTVR-- 310
            :.|..|::...:.|. :..|:.:|||.|....|......|..|            |.|...|.
Frog   616 DVLLLHYENAHEAQACEVKQELNHQHGADGQPSIKESKEHSCTKCDFIVQVEEDLSRHYRRVHNC 680

  Fly   311 FVTEDVRFTTAGPET------SASNMYYDVPVVDGSVH------ANESKTYADLGNAYAPFPPSS 363
            :......||.|..::      ||.....::...:|..|      ..|.||...:.|..||
Frog   681 YKCRQCNFTAADTQSLLDHFNSAHCQESEITTSNGGEHHGASSIKEEPKTDLKVYNLVAP----- 740

  Fly   364 SFSSNSYAATLQQGNTIYSVPGTGQFLAKSESGLNQTGLLRQTGPATFQTISFEGGNGIEPLWAS 428
                     ..:.|..|:......:.|...|:       ||                  |..|:.
Frog   741 ---------DSKMGEAIFDSTVKKEKLEDKET-------LR------------------EKSWSD 771

  Fly   429 PAPPEYQSVQFSNFHPQVIDEYGSGNMSTSHWPPASSIGQYDGSLVTA--------SSTSSPNHE 485
            .|..:.:.|.:.  .|.:        :.||  |..|.:|.  |.|.|.        ||..|||.|
Frog   772 SAVDDLRGVAWR--APDI--------LRTS--PSYSQMGL--GLLTTVSVNQEQQKSSRDSPNVE 822

  Fly   486 ------------LKCENCHGPFLRKGSEYFCPNCPAFMRMAPRITQRQAKPKAAAAPNNRR-NGV 537
                        ::.:...|.......|....:.|.:    |.....::|.::.:....|| :||
Frog   823 AAHLARPLYGLSIESKGFQGVTAGASGEKSGQHTPQY----PTAGDGKSKDESQSLLRRRRGSGV 883

  Fly   538 TCANCQTNSTTLWRRNNEGNPVCNACGLYYKLHNMNRPLSMKKEG-----IQKRKRKPKNNGGAP 597
            .||||.|..|:|||:|..|..||||||||.|||:..|||::.|:.     |::|.||..|
Frog   884 FCANCLTTKTSLWRKNANGGYVCNACGLYQKLHSTPRPLNIIKQNNGEQIIRRRTRKRLN----- 943

  Fly   598 MHRAPLPSMSQGVNLMANSPLYPSQVPVSMLNSQLNSQQNSSPELHDMSTTGQAGG----QRVVS 658
                                      |.::...|||..|..|.|       .||.|    :|...
Frog   944 --------------------------PEALQPEQLNKHQRPSSE-------EQANGSPLERRSED 975

  Fly   659 ISLNATAPPTPDGTLNMSARHHVTGESHSPYSQQSTPQSQSPHLPGTVPINRQIVQPVP-TIESS 722
            .|:..........::|.........:|||  :||:...||      |:.|::: :||:. .|:|.
Frog   976 HSMEGHQRENQQLSMNKYESQASLTKSHS--AQQTMIVSQ------TMDIHKR-MQPLHIQIKSP 1031

  Fly   723 RSSNTE--LTPSVITRTGLPERSS 744
            :.|:.|  .:.||....|..||.|
Frog  1032 QESSGEPGNSSSVSDGKGSSERGS 1055

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GATAe	NP_650516.2	ZnF_GATA	534..583	CDD:214648	29/54 (54%)
GATAe	NP_650516.2	ZnF_GATA	538..589	CDD:238123	28/55 (51%)
trps1	XP_004915118.1	ZnF_GATA	884..940	CDD:238123	28/55 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910