DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GATAe and ZGLP1

DIOPT Version :9

Sequence 1:	NP_650516.2	Gene:	GATAe / 41945	FlyBaseID:	FBgn0038391	Length:	746	Species:	Drosophila melanogaster
Sequence 2:	NP_001096637.1	Gene:	ZGLP1 / 100125288	HGNCID:	37245	Length:	271	Species:	Homo sapiens

Alignment Length:	181	Identity:	42/181 - (23%)
Similarity:	58/181 - (32%)	Gaps:	72/181 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly   412 QTISFEGGNGIEPLWASPAPPE-------------------YQSVQFS-NFHP----QVIDEYGS 452
            ||...:.|..::|.....|||:                   ::.|... ...|    |:|..|..
Human   103 QTRISQKGRRLQPPGTPSAPPQRRPRKQLNPCRGTERVDPGFEGVTLKFQIKPDSSLQIIPTYSL 167

  Fly   453 GNMSTSHWPPASSIGQYDGSLVTASSTSSPNHELKCENCHGPFLRKGSEYFCPNCPAFMRMAPRI 517
            ...|.|...||.::|                         ||....|.
Human   168 PCSSRSQESPADAVG-------------------------GPAAHPGG----------------- 190

  Fly   518 TQRQAKPKAAAAPNNRRNGVTCANCQTNSTTLWRRNNEGNPVCNACGLYYK 568
            |:..:....|..|  ||    ||:|:|..|.|||...:|.|:|||||:.||
Human   191 TEAHSAGSEALEP--RR----CASCRTQRTPLWRDAEDGTPLCNACGIRYK 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GATAe	NP_650516.2	ZnF_GATA	534..583	CDD:214648	18/35 (51%)
GATAe	NP_650516.2	ZnF_GATA	538..589	CDD:238123	17/31 (55%)
ZGLP1	NP_001096637.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	18..40
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	96..141		7/37 (19%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	170..199		9/70 (13%)
		ZnF_GATA	202..>240	CDD:214648	20/40 (50%)
		GATA	206..240	CDD:278735	17/30 (57%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5641
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810