Protein Alignment srp and Gata4

DIOPT Version :10

• Sequence 1: NP_732100.2
• Gene: srp / 41944
• FlyBaseID: FBgn0003507
• Length: 1264
• Species: Drosophila melanogaster
• Sequence 2: NP_001297539.1
• Gene: Gata4 / 14463
• MGIID: 95664
• Length: 442
• Species: Mus musculus
• Alignment Length: 498
• Identity: 140/498 - (28%)
• Similarity: 176/498 - (35%)
• Gaps: 181/498 - (36%)

  Fly   607 YGSPRSSHSGGGGGGTLPAFQRIAYPNSGSVERYAPI----TNYRGQNDTWFDPLSY-------- 659
            :|.|..::..||.|    ||...|...|..|  |.|.    ::..|        |||
Mouse    11 HGPPPGAYEAGGPG----AFMHSAGAASSPV--YVPTPRVPSSVLG--------LSYLQGGGSAA 61

  Fly   660 --ATSSSGQAQLG-VGVGAGVV------SNVIRNGRAISAANAAAAAAADGTTGRVDPGTFLSAS 715
              .|:|.|.:..| .|.|.|..      |.....|.|.:....:...:..||||.:  ....:|:
Mouse    62 AAGTTSGGSSGAGPSGAGPGTQQGSPGWSQAGAEGAAYTPPPVSPRFSFPGTTGSL--AAAAAAA 124

  Fly   716 ASLSAMAAESGGDFYKPNSFNVGGGGRSKANTSGAASSYSCPGSNATSAATSAVASGTAATAATT 780
            |:..|.|..|||     .:...|..||.:....|.|.|||.| ..|..|...|..:..||.:|..
Mouse   125 AAREAAAYGSGG-----GAAGAGLAGREQYGRPGFAGSYSSP-YPAYMADVGASWAAAAAASAGP 183

  Fly   781 LDEHV-----SRAN--------------------------------------------------- 789
            .|..|     .|||
Mouse   184 FDSPVLHSLPGRANPGRHPNLVDMFDDFSEGRECVNCGAMSTPLWRRDGTGHYLCNACGLYHKMN 248

  Fly   790 ---------SRRLSASKRAGLSCSNCHTTHTSLWRRNPAGEPVCNACGLYYKLHSVPRPLTMKKD 845
                     .||||||:|.||||:||.||.|:|||||..|||||||||||.|||.|||||.|:|:
Mouse   249 GINRPLIKPQRRLSASRRVGLSCANCQTTTTTLWRRNAEGEPVCNACGLYMKLHGVPRPLAMRKE 313

  Fly   846 TIQKRKRKPKGTKSEK-------------SKSKSKNALNAIMESGSLVTNCHNVGVVLDSSQMDV 897
            .||.||||||.....|             |.:.|.|:.||...|.|
Mouse   314 GIQTRKRKPKNLNKSKTPAGPAGETLPPSSGASSGNSSNATSSSSS------------------- 359

  Fly   898 NDDMKPQLDLKPYNSYSSQPQQQLPQYQQQQQLLMADQHSSAASSPHSMGSTSLSPSAMSHQHQT 962
            :::|:|   :|.....||       .|          .|||:.|...|        :...|....
Mouse   360 SEEMRP---IKTEPGLSS-------HY----------GHSSSMSQTFS--------TVSGHGPSI 396

  Fly   963 HPHQQQQQQLCSGLDMSPNSNYQMSPLNMQQHQQQQSCSMQHS 1005
            ||       :.|.|.:||..  ..||:.    |..|:.|.|.|
Mouse   397 HP-------VLSALKLSPQG--YASPVT----QTSQASSKQDS 426

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
srp	NP_732100.2	ZnF_GATA	802..853	CDD:238123	37/50 (74%)
Gata4	NP_001297539.1	GATA-N	1..204	CDD:461628	57/214 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	60..107		10/46 (22%)
		ZnF_GATA	216..266	CDD:238123	6/49 (12%)
		ZnF_GATA	270..321	CDD:238123	37/50 (74%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	314..393		27/125 (22%)