Protein Alignment srp and Gata2

DIOPT Version :10

• Sequence 1: NP_732100.2
• Gene: srp / 41944
• FlyBaseID: FBgn0003507
• Length: 1264
• Species: Drosophila melanogaster
• Sequence 2: NP_032116.4
• Gene: Gata2 / 14461
• MGIID: 95662
• Length: 480
• Species: Mus musculus
• Alignment Length: 522
• Identity: 134/522 - (25%)
• Similarity: 185/522 - (35%)
• Gaps: 141/522 - (27%)

  Fly   519 MQSPNQTQAHLQQQHHQQQQQQHQQHQQ-----------QQLQQQQQQHHHNQHQHHNSSSSSPG 572
            |..|....|.....||......:.:..|           ..|..|...::.|........|.||.
Mouse    11 MAHPAVLNAQHPDSHHPGLAHNYMEPAQLLPPDEVDVFFNHLDSQGNPYYANPAHARARVSYSPA 75

  Fly   573 PAGL--------H--HSSSSAATAAAVAAATAAVNGHNS--------------SLEDGYGSPRSS 613
            .|.|        |  ||..........||.:||...|:|              |.....|.|.|.
Mouse    76 HARLTGGQMCRPHLLHSPGLPWLDGGKAALSAAAAHHHSPWTVSPFSKTPLHPSAAGAPGGPLSV 140

  Fly   614 H---SGGGGGGTLPAFQRIAYPNSGSVERYAPITNYRGQNDTWFDP-----LSYATSSSGQAQ-L 669
            :   :||.|||           :..||....|...:.|.:...|.|     :|...|::|.|. .
Mouse   141 YPGAAGGSGGG-----------SGSSVASLTPTAAHSGSHLFGFPPTPPKEVSPDPSTTGAASPA 194

  Fly   670 GVGVGAGVVSNVIRNGRAISAANAAAAAAADGTTGRVDPGTFLSASAS----------LSAMAAE 724
            ....|..|.....::|.....:.:.:.....|:..|....|..:..|:          :.|.|.:
Mouse   195 SSSAGGSVARGEDKDGVKYQVSLSESMKMEGGSPLRPGLATMGTQPATHHPIPTYPSYVPAAAHD 259

  Fly   725 SGGDFYKPNSFNVGGGGRSKANTSGAASSYSCPGSNATSAATSAVASGTAATA------------ 777
            .|...:.|..|.  ||..|.......:.:.||      |.....|..|..||.
Mouse   260 YGSSLFHPGGFL--GGPASSFTPKQRSKARSC------SEGRECVNCGATATPLWRRDGTGHYLC 316

  Fly   778 -ATTLDEHVSRAN------SRRLSASKRAGLSCSNCHTTHTSLWRRNPAGEPVCNACGLYYKLHS 835
             |..|...::..|      .|||||::|||..|:||.||.|:|||||..|:|||||||||||||:
Mouse   317 NACGLYHKMNGQNRPLIKPKRRLSAARRAGTCCANCQTTTTTLWRRNANGDPVCNACGLYYKLHN 381

  Fly   836 VPRPLTMKKDTIQKRKRKPKGTKSEKSKSKSK--NALNAIMESGSLVTNCHNVGVVLDSSQMDVN 898
            |.|||||||:.||.|.|| ..:||:|||..::  ..|:..|:..|
Mouse   382 VNRPLTMKKEGIQTRNRK-MSSKSKKSKKGAECFEELSKCMQEKS-------------------- 425

  Fly   899 DDMKPQLDLKPYNSYS----SQPQQQLPQYQQQQQLLMADQ--HSSAASS---PHSMGSTSLSPS 954
                     .|:::.:    ..|...||.:.....:|....  |.|::.|   ||        ||
Mouse   426 ---------PPFSAAALAGHMAPVGHLPPFSHSGHILPTPTPIHPSSSLSFGHPH--------PS 473

  Fly   955 AM 956
            :|
Mouse   474 SM 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
srp	NP_732100.2	ZnF_GATA	802..853	CDD:238123	36/50 (72%)
Gata2	NP_032116.4	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	166..208		9/41 (22%)
		ZnF_GATA	294..344	CDD:238123	12/49 (24%)
		ZnF_GATA	349..398	CDD:238123	36/48 (75%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	457..480		8/27 (30%)