DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment srp and ZGLP1

DIOPT Version :9

Sequence 1:	NP_732100.2	Gene:	srp / 41944	FlyBaseID:	FBgn0003507	Length:	1264	Species:	Drosophila melanogaster
Sequence 2:	NP_001096637.1	Gene:	ZGLP1 / 100125288	HGNCID:	37245	Length:	271	Species:	Homo sapiens

Alignment Length:	165	Identity:	45/165 - (27%)
Similarity:	61/165 - (36%)	Gaps:	49/165 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   703 TGRVDPGTFLSASASLSAMAAESGGDFYKPNSFNVGGGGRSKANTSGAASSYSCPGSNATSAATS 767
            |.||||| |...:....          .||:|            :.....:||.|.|:.:..:.:
Human   137 TERVDPG-FEGVTLKFQ----------IKPDS------------SLQIIPTYSLPCSSRSQESPA 178

  Fly   768 AVASGTAATAATTLDEHVSRANSRRLSASKRAGLSCSNCHTTHTSLWRRNPAGEPVCNACGLYYK 832
            ....|.||....| :.|  .|.|..|...:     |::|.|..|.|||....|.|:|||||:.||
Human   179 DAVGGPAAHPGGT-EAH--SAGSEALEPRR-----CASCRTQRTPLWRDAEDGTPLCNACGIRYK 235

  Fly   833 LHS--------VPRPLTMKK----------DTIQK 849
            .:.        |||.....|          |.||:
Human   236 KYGTRCSSCWLVPRKNVQPKRLCGRCGVSLDPIQE 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
srp	NP_732100.2	ZnF_GATA	798..847	CDD:214648	21/66 (32%)
srp	NP_732100.2	ZnF_GATA	802..853	CDD:238123	23/66 (35%)
ZGLP1	NP_001096637.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	18..40
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	96..141		2/3 (67%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	170..199		7/31 (23%)
		ZnF_GATA	202..>240	CDD:214648	16/42 (38%)
		GATA	206..240	CDD:278735	16/33 (48%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165140999
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5641
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740