Protein Alignment Hel89B and smarcad1b

DIOPT Version :10

• Sequence 1: NP_732097.2
• Gene: Hel89B / 41943
• FlyBaseID: FBgn0022787
• Length: 1923
• Species: Drosophila melanogaster
• Sequence 2: XP_005155692.3
• Gene: smarcad1b / 563175
• ZFINID: ZDB-GENE-091113-61
• Length: 955
• Species: Danio rerio
• Alignment Length: 994
• Identity: 264/994 - (26%)
• Similarity: 430/994 - (43%)
• Gaps: 192/994 - (19%)

  Fly   984 DQVCDRNPSPNSKILNNLCTLLR-----SDPEFTPKLVMPLETLKQTPVSSEVINNCVYYGILTL 1043
            |.|....|.......::|.|.:.     ||.|.:...:||:..|:  |...:..::...|.: :.
Zfish    21 DSVIPETPETKRPSGSSLSTAISDSDSDSDSEISGSSMMPVRKLR--PRKRKAASSADEYSV-SD 82

  Fly  1044 ALQQTVTTTNTRSGAGGATTPTATTAPRGPGRPPTGEILSATNATAHIELKAQQAKEAEAKQCRI 1108
            ..::.|..|..|......|..|:..|.  |......|  :.|:......||......|::.|.|.
Zfish    83 EEEEIVVKTKRRPTHSRTTRSTSQQAQ--PAHQKASE--TVTDIAHPSPLKTSGMAAADSVQQRR 143

  Fly  1109 QRLGAACAIEKLCRIFG------------------EQIIEKV-AVFQHLMFGKVEQFVKEAYDWR 1154
            ::.....:.|...|..|                  |:::.|: ..|.||...::...::| :||.
Zfish   144 RQQMCGSSQESDSRKGGRVSAADDSEEEGQRSKDQERMLRKLQRKFPHLNKNELRDVLQE-HDWL 207

  Fly  1155 LGSLLPDLGVCNELV--SSMQLIETAAPHLH----VALHPQMFALLPSLGFIVCHPLKAVRHMAA 1213
            :...|..|.:.::||  |.....:|:.|..|    ....||  |.:..|.    .|.|.   ..:
Zfish   208 IDDALETLRMFSDLVVESEDDSSQTSTPAKHTRRVAETRPQ--AQVTKLS----SPPKP---KPS 263

  Fly  1214 RCIAVLAEIDACQTMQFVVHDLLPLLGKI------EQLIERQGAI---------EAIERVVSRLQ 1263
            |      .:|..:|.|.:...  |:|.|.      |:..:.:.::         :..|..:|:|:
Zfish   264 R------PLDGTRTSQRIAKQ--PILAKYTYVSSEEECSDSEASVVNGLLDSDSDQSEETLSKLK 320

  Fly  1264 IKVVPYIVLLVVPLLGAMS--------------------DPDESVRL---LSTHCFANLVQLMP- 1304
            .:::.:.....|..|..::                    |.|:::|.   ||....|...:::.
Zfish   321 TEILCFFQSASVDELTLIAGCSLKKAQKITELRPFKTWKDLDDAMRRRNGLSAELLAGCREVLKE 385

  Fly  1305 ------LDGKTEQLKSDPLQ-ARKTRDREFLDYLFNPKSIPNYKVPVPISVELRCYQQAGINWLW 1362
                  |..|.|::....:| ..:..|:       .|.|:...:: :..:.:|:.||..|:|||.
Zfish   386 REVVKGLMSKCEEISVKLIQDVTQVMDK-------GPGSMTQPEI-LSSTFQLKPYQLIGLNWLV 442

  Fly  1363 FLNKYNLHGILCDDMGLGKTLQTICILAGDHMHRQTANLANLPSLVICPPTLTGHWVYEVEKFLD 1427
            .|::..|.|||.|:||||||:|.|..||  |:: |..|  :.|.|:..|.:...:||.|:..:..
Zfish   443 LLHQNKLSGILADEMGLGKTIQAISFLA--HLY-QEGN--HGPHLITVPASTLDNWVRELNLWCP 502

  Fly  1428 QGSVLRPLHYYGFPVGREKLRSDIGTKC---NLVVASYDTV---RKDIDFFSGIHFNYCVLDEGH 1486
            ...|   |.|||....|:.:|.:|..:.   |::|::|:..   ..|...|..:...|.|.||||
Zfish   503 SFKV---LVYYGSADDRKYMRYEILNQIVEYNIIVSTYNLAIGNSSDRSLFCKLKLEYAVFDEGH 564

  Fly  1487 IIKNGKTKSSKAIKRLKANHRLILSGTPIQNNVLELWSLFDFLMPG-FLGTEKQFVQRFSRPILS 1550
            ::||..:...:.:..:.|.:||:|:|||:|||:|||.||.:|:||. |..:..|..:.||
Zfish   565 LLKNMNSLRYRHLMAINAKYRLLLTGTPLQNNLLELMSLLNFIMPNMFSSSTSQIAKMFS----- 624

  Fly  1551 SRDAKSSAKEQEAGVLAMEALHRQVL--PFLLRRVKEDVLKDLPPKITQDLLCELSPLQLRLYED 1613
               .|||  |:::........|.:::  ||:|||||.:|||.||.|..|...|.:|..|..||..
Zfish   625 ---MKSS--EEQSSFERDRITHAKLIMKPFILRRVKSEVLKQLPAKEEQVEFCAMSERQQELYSA 684

  Fly  1614 FSNKHLKDCLDKLGDSSSASMVTENLSAKTHIFQALRYLQNVCNHPKLVLRQ--SEELTKVTSQL 1676
            .        |.||..||:..        |..:...:..|:.:.||| |:.||  :.|..|..|:|
Zfish   685 L--------LHKLKHSSNGE--------KRELTNVMMQLRKMSNHP-LLHRQFYTTEKLKAMSKL 732

  Fly  1677 ALSNSS---------------LDDIE-----------HSAKLPALKQLLLDCG-IGVQTESVSQ- 1713
            .|...|               |.|.|           |..:|..  .:|||.| :.:.|:.::.
Zfish   733 MLKEPSHRDADPALIKEDMEVLSDFELHRLCQQYSALHEYQLNT--DVLLDSGKLSLLTQLLNSL 795

  Fly  1714 ----HRALIFCQLKAMLDIVEQDLLRRHLPSVTYLRLDGSVPASQRQDIVNNFNSDPSIDVLLLT 1774
                .|.::|.|...||||:|. .||.|  ...|.|||||.|.|.|..:::.||:|..|.|.||:
Zfish   796 KEKGDRVVLFSQFTMMLDILEV-FLRHH--KHRYNRLDGSTPMSDRIGLIDQFNTDQDIFVFLLS 857

  Fly  1775 TMVGGLGLNLTGADTVIFVEHDWNPMKDLQAMDRAHRIGQKKVVNVYRLITRNSLEEKIMGLQKF 1839
            |..||||:|||.|:.||..:.|.||..|.||..|.||:||.|.|.|.:||:::|:|:.::.:.:.
Zfish   858 TRAGGLGINLTSANVVILHDIDCNPYNDKQAEGRCHRVGQTKTVKVIKLISKDSIEDTMLRIGER 922

  Fly  1840 KILTANTVVSAENASLQTM 1858
            |:.....:.:.::....|:
Zfish   923 KLKLEQEMTATQDGEEDTL 941

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hel89B	NP_732097.2	HEAT repeat	5..30	CDD:293787
		HEAT repeat	42..70	CDD:293787
		HEAT repeat	395..420	CDD:293787
		HEAT repeat	433..465	CDD:293787
		HEAT repeat	475..504	CDD:293787
		HEAT repeat	516..540	CDD:293787
		HEAT repeat	560..589	CDD:293787
		DUF3535	654..1138	CDD:463447	33/177 (19%)
		HepA	<1342..1849	CDD:440319	185/549 (34%)
smarcad1b	XP_005155692.3	CUE	179..215	CDD:270465	9/36 (25%)
		ComEA	<329..377	CDD:441164	7/47 (15%)
		HepA	<429..926	CDD:440319	185/536 (35%)