DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mor and Mysm1

DIOPT Version :9

Sequence 1:	NP_524373.1	Gene:	mor / 41942	FlyBaseID:	FBgn0002783	Length:	1209	Species:	Drosophila melanogaster
Sequence 2:	XP_017175747.1	Gene:	Mysm1 / 320713	MGIID:	2444584	Length:	824	Species:	Mus musculus

Alignment Length:	381	Identity:	92/381 - (24%)
Similarity:	150/381 - (39%)	Gaps:	89/381 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   237 ESPAERWRVSASWIVDLEQYNEWMAEEDYEVDEQG---------------KKKTHKQ-----RMS 281
            :|||:....|..|.|           |:.|:.|||               |.:|..|     |..
Mouse   106 DSPAKPASHSVKWTV-----------EEKELFEQGLAKFGRRWTKIATLLKSRTVLQVKSYARQY 159

  Fly   282 IDDIMSFGDEKKKPAASSGGGKQKRRRSPSPASSASTSKPGKRKRSPAVVHKKSRNDDDDEDLTR 346
            ..:.:.:..||:.|...|....|.:.:.....:.|:....|........|..:..:||:|.|:|.
Mouse   160 FKNKVKWDVEKETPTQKSSSDLQVKNKDDRTKAWAAACLRGSADPCLNAVKIEKLSDDEDVDITD 224

  Fly   347 DLDDPPAEPNVQE-----VHKANAALQST-----ASPAPGGKSRGDNDMMPIKGGTMTDLDDEMT 401
            :||:..::.:...     :...|:.:.:|     ....|..||.|:: :..:|.|       |..
Mouse   225 ELDELTSQTSQNSGSHLTLDVPNSKMYTTNQGELCQEGPLAKSSGES-LQNVKQG-------EGE 281

  Fly   402 GGSAAQAMSTGDGENSQTGKTSDNSNTQ-------------EFSSSAK----------EDMEDN- 442
            ..|:::..|..:.:.| |.|.|...|.:             |....||          :|...|
Mouse   282 ACSSSEIASWAEKQKS-TDKNSAELNEKYNKVVEEHTLHRGEVREEAKHSPSPEPCERQDSSGNE 345

  Fly   443 -------VTEQTH---HIIVPSYSAWFDYNSIHVIEKRAMPEFFNSKNKSKTPEIYMAYRNFMID 497
                   :.|:.|   .:..|......|.|.|...||:|:||||..: ::||||.|:..||:::|
Mouse   346 MLLPPCQIEEENHEGEELKPPEQEVEIDRNVIQEEEKQAIPEFFEGR-QTKTPERYLKIRNYILD 409

  Fly   498 TYRLNPTEYLTSTACRRNL--AGDVCAIMRVHAFLEQWGLINYQIDADV--RPTPM 549
            .:.:...:||..|:.|..|  .|||..|.|:|.:||..|.||:..:..|  ||.|:
Mouse   410 QWEICKPKYLNKTSVRPGLKNCGDVNCIGRIHTYLELIGAINFGCEQAVYNRPQPL 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mor	NP_524373.1	SWIRM-assoc_2	6..446	CDD:293105	51/269 (19%)
		RSC8	417..>742	CDD:227584	51/171 (30%)
		SWIRM	453..538	CDD:282311	34/86 (40%)
		SWIRM-assoc_3	738..801	CDD:293107
		SWIRM-assoc_1	962..1031	CDD:293104
Mysm1	XP_017175747.1	Myb_DNA-binding	116..160	CDD:365977	11/54 (20%)
		SWIRM	373..452	CDD:367940	33/79 (42%)
		MPN_2A_DUB	562..749	CDD:163698
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5259
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900