DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mor and Mysm1

DIOPT Version :9

Sequence 1:	NP_524373.1	Gene:	mor / 41942	FlyBaseID:	FBgn0002783	Length:	1209	Species:	Drosophila melanogaster
Sequence 2:	XP_008762133.1	Gene:	Mysm1 / 298247	RGDID:	1311787	Length:	811	Species:	Rattus norvegicus

Alignment Length:	385	Identity:	93/385 - (24%)
Similarity:	153/385 - (39%)	Gaps:	107/385 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   238 SPAERWRVSASWIVDLEQYNEWMAEEDYEVDEQG---------------KKKTHKQ-----RMSI 282
            |||:....|..|.:           |:.::.|||               |.:|..|     |...
  Rat   107 SPAKPSSYSVKWTI-----------EEKKLFEQGLAKFGRRWTKIAALVKSRTVLQVKSYARQYF 160

  Fly   283 DDIMSFGDEKKKPAASSGGGKQKRRRSPSP----ASSASTSKPGKRKRSPAVVHKKSRNDDDDED 343
            .:.:.:|.||:.|...|....|.:.:....    ||..:.:          .|..:..:||:|.|
  Rat   161 RNKVKWGAEKETPTLKSNSDLQVKNKDERTKVWVASDPNLN----------AVKIEKLSDDEDVD 215

  Fly   344 LTRDLDDPPAEPNVQ-------------EVHKAN-AALQSTASPAPGGKSRGDNDMMPIKGGTMT 394
            :|.:||:..::.:.:             :::|.| ..|....|.|   ||..:| :..:|
  Rat   216 ITDELDELTSQTSQKNYGGHLTLDVPSSKMYKTNQGELCQEGSLA---KSAEEN-LQNVK----- 271

  Fly   395 DLDDEMTGGSAAQAMSTGDGENSQTGKTSDNSN-------------TQEFSSS-------AKEDM 439
              ..|....|:::.||..:.:|: .||.|...|             |:|...|       .::|.
  Rat   272 --QSEAEACSSSEIMSWAEKQNN-NGKNSVELNEKYSKLVEEYTMLTEETKHSPSPEPCEGQKDP 333

  Fly   440 EDN--------VTEQTH---HIIVPSYSAWFDYNSIHVIEKRAMPEFFNSKNKSKTPEIYMAYRN 493
            ..|        |.|:.|   .:..|......|.|.|...||:|:||||..: ::||||.|:..||
  Rat   334 RGNELLLPPCQVEEENHEGEELKPPEQEVEIDRNVIQEEEKQAIPEFFEGR-QTKTPERYLKIRN 397

  Fly   494 FMIDTYRLNPTEYLTSTACRRNL--AGDVCAIMRVHAFLEQWGLINYQIDADV--RPTPM 549
            :::|.:.:...:||..|:.|..|  .|||..|.|:|.:||..|.||:..:..:  ||.|:
  Rat   398 YILDQWEICKPKYLNKTSVRPGLKNCGDVNCIGRIHTYLELIGAINFGCEQAIYNRPQPV 457

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mor	NP_524373.1	SWIRM-assoc_2	6..446	CDD:293105	53/273 (19%)
		RSC8	417..>742	CDD:227584	50/168 (30%)
		SWIRM	453..538	CDD:282311	34/86 (40%)
		SWIRM-assoc_3	738..801	CDD:293107
		SWIRM-assoc_1	962..1031	CDD:293104
Mysm1	XP_008762133.1	Myb_DNA-binding	116..160	CDD:395191	9/54 (17%)
		SWIRM	365..444	CDD:398234	33/79 (42%)
		MPN_2A_DUB	554..736	CDD:163698
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5259
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900