Protein Alignment Rbf2 and rbl2

DIOPT Version :10

• Sequence 1: NP_524372.1
• Gene: Rbf2 / 41941
• FlyBaseID: FBgn0038390
• Length: 783
• Species: Drosophila melanogaster
• Sequence 2: XP_002937369.2
• Gene: rbl2 / 100490373
• XenbaseID: XB-GENE-1012835
• Length: 1089
• Species: Xenopus tropicalis
• Alignment Length: 1095
• Identity: 221/1095 - (20%)
• Similarity: 395/1095 - (36%)
• Gaps: 379/1095 - (34%)

  Fly     5 EVEGE---AETLVR-RFSVSCEQLELEARIQQSALSTYHRLDAVNGLSTSEADAQEWLCCAVYSE 65
            |.|||   ||..:| |:...|..|.::.|.:..|...|.|   ::...|.|.:|..||.|::|..
 Frog     6 EEEGEGKQAEEQLRCRYDELCSSLNMDERARGEAWEYYSR---ISQNYTLEGNALHWLACSLYVA 67

  Fly    66 LQRSKMRDIRESINEANDSVAKNCCWNVSLTRLLRSFKMNVSQFLRRMEHWNWLTQNENTFQLEV 130
            . |..:..:.....|.|         .||||::|.|.::::.:|..:::.|..:......|:...
 Frog    68 C-RQTVPTVGRGTVEGN---------YVSLTQILSSSELSLIEFFNKIKKWEDMANLPTEFRTRT 122

  Fly   131 EELRCRLGITSTLLRHYKHIFRSLFVHPGKGADPGAANH-----------YQALYEFGWLLFLVI 184
            ::|.....:::.|.:.|..||:.:|..|   .:.....|           ...:|:|.|:||:..
 Frog   123 KKLERNFTVSAVLFKKYDPIFQEVFRSP---LEEQPRQHRGRKQRRQPCTVSEVYQFCWVLFIHT 184

  Fly   185 RNELPGFAITNLINGCQVLVCTMDLLFVNALEVP-RSVVIRREFSGVPKNWDTEDFN-PILLNKY 247
            :...|..: .:|:|...:|:|.:||::.|||:.| |..::...|.|:|:::.:.::. |  |...
 Frog   185 KGNFPMIS-DDLVNSYHLLLCALDLVYGNALQCPNRRELLNPNFQGLPEDFCSREYKAP--LEAP 246

  Fly   248 SVLEALGELIP--ELPAKGVVQMKNAFFHKALIMLYMDHSLVGDDTHMREIIKEGMLDINLENLN 310
            .::|.|..|..  .|.|||:   |..|:...:..|:....|.|....:...:..|....:::.:|
 Frog   247 CIIETLCGLHDGLVLEAKGI---KEHFWKPYIRKLFDKKILKGKSDSLVGFLDPGNFADSVKAIN 308

  Fly   311 RKYTNQVADISEMDERVLL---------------------SVQGA-----IETKGDSPKSPQLAF 349
            :.|...|.....:||||.:                     ||:.|     ::...|..||.:::.
 Frog   309 KAYEGYVLSAGNLDERVFMEDVEEEIGRIGQCLNPSLGMESVERAKVTYNLQQNFDKFKSLRVST 373

  Fly   350 QTSSSPSHRKLSTHDLPASLPLS-----------IIKAFPKKEDADKIVNYL-----DQT----- 393
            ..:|....|:.|    |.:.|:|           |:..| |...:::::..|     |.|
 Frog   374 PLTSLKYIRECS----PCTTPISSAMYCVSRLFTILTGF-KPAPSERLLQMLRSCSRDPTKTILR 433

  Fly   394 -LEEMNRTF-----TMAVKDFLDAELSGKRFRQARGLYYKYLQKILGPELVQKPQLKIGQLMKQR 452
             |:||:.||     ::|.|.|. .:::.|.||.|..||||.|:.::..|..:...:.:..:::|.
 Frog   434 RLKEMSETFCENTDSVAEKQFC-RDITKKYFRLAEVLYYKVLESVIDQEKKRLGDIDMSSILEQD 497

  Fly   453 KLTAALLACCLELALHVHHKLVEGLRFPFVLHCFSLDAYDFQKILELVVRYDHGFLGRELIKHLD 517
            ....:|::||||:.:..:..  .| .||.::..|.|..|.|.|::|:|::.:.| |.||::|||:
 Frog   498 VFHRSLMSCCLEITVFSYKP--PG-NFPSIIVMFELAPYQFYKVIEVVIKAEEG-LCREVVKHLN 558

  Fly   518 VVEEMCLDSLIFRKSSQLWWELNQ---RLPRYKEV------------------------------ 549
            .:||..|:.:.:...|.||.::.:   ::|..:||
 Frog   559 NIEEQILECMAWTHDSPLWDKIRENDGKIPLCEEVLHPQHFEKSGDNGTTGSLTPRRINEIRADA 623

  Fly   550 ----------------------------------DAETE-------------------------- 554
                                              |:.:|
 Frog   624 SGLGRSVPSSPATLCDRYSSPAAGTARRRLFVDPDSSSEAGSPAQASPLATDTVATPPVPGQTLV 688

  Fly   555 ----------------------------------------------------------------- 554
                                                                             
 Frog   689 TMATATVTANNGQTVTIPVQGIANENGGITFFPVQVNVSSQPHSVTSSVPPLTAQALAGPLNPQQ 753

  Fly   555 -----------------DKENFST----GSSICL--RKFYGLANRRLLLLCKSLCLVDSF-PQIW 595
                             .|:|.::    .||:.|  |:.|.||:.||..||..|.:.|.. .:||
 Frog   754 IQGQVSVSQVPASPGQQSKQNLTSKLKKASSLTLFCRRVYCLASIRLKDLCLKLDISDELRRKIW 818

  Fly   596 HLAEHSFTLESSRLLRNRHLDQLLLCAIHLHVRLEKLHLTFSMIIQHYRRQPHFRRSAYREVSL- 659
            ...|.|. :....|:::|||||||:||:::..::.|...:|..|::.||.|||.....||.|.|
 Frog   819 TCFEFSL-VHCPELIKDRHLDQLLMCAVYVITKVTKEDTSFHNIMKCYRVQPHASSHVYRSVLLK 882

  Fly   660 -----------------------------------------------------------GNG--- 662
                                                                       |:.
 Frog   883 KRRRRQSGSSDHILQPGSPAENTKDICSREPSPVMRSSSTLPVPQPNSAPPTPTRITAAGSNFVE 947

  Fly   663 -QTADIITFYNSVYVQSMGNYGRHLECAQTRKSLEESQSNVGILTETTSNELSMRANISISSPPP 726
             :..|::.|||::|::.:.::           ::..||||       ||....:....||.:..|
 Frog   948 EERGDLVQFYNNIYIEKIKSF-----------AMRFSQSN-------TSEATPLSPYPSIRAVSP 994

  Fly   727 PRV----CQSGSCSSHPPSSPAASPLS-----LQSSPNVKRAASSNDLMREIKRP 772
            .|:    ..|...|:|...:....|..     ...|| .||....|.::|..:.|
 Frog   995 RRIQLSHIHSIYVSTHNDDATTVCPREKICYYFDLSP-AKRLQEINSMIRTGETP 1048

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rbf2	NP_524372.1	DUF3452	83..213	CDD:463402	29/140 (21%)
		RB_A	<384..536	CDD:460364	48/167 (29%)
		RB_B	<593..679	CDD:460363	32/149 (21%)
rbl2	XP_002937369.2	CYCLIN_SF	23..107	CDD:410207	23/96 (24%)
		DUF3452	78..212	CDD:463402	31/146 (21%)
		RB_A	389..580	CDD:460364	55/196 (28%)
		SP1-4_N	<606..>787	CDD:425404	6/180 (3%)
		CYCLIN_RBL2	784..972	CDD:410309	44/199 (22%)