DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5516 and ZCCHC10

DIOPT Version :9

Sequence 1:	NP_001189228.1	Gene:	CG5516 / 41940	FlyBaseID:	FBgn0038389	Length:	176	Species:	Drosophila melanogaster
Sequence 2:	NP_001295056.1	Gene:	ZCCHC10 / 54819	HGNCID:	25954	Length:	202	Species:	Homo sapiens

Alignment Length:	150	Identity:	66/150 - (44%)
Similarity:	90/150 - (60%)	Gaps:	10/150 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 IRCQKCLQIGHWSYECKEKRKYVHRSSRTKQLSKRMSQKEADAPKNQVEEHSEVASS--EGKKVR 90
            :||||||:.|||:|||..||||:||.|||.:|.|.:.:||     |::.....:..:  |.|..:
Human    53 VRCQKCLEFGHWTYECTGKRKYLHRPSRTAELKKALKEKE-----NRLLLQQSIGETNVERKAKK 112

  Fly    91 RKRKTSKSSSSSSSSSDSSDSSSESGSSSESDSSSSSSDSDDEEGSSSDSSGSGSDSDSSEDQKQ 155
            ::.|:..|||||||.|.:||||||   |.|:.:||||.|||.:|.|||.||.:.|.:.||.....
Human   113 KRSKSVTSSSSSSSDSSASDSSSE---SEETSTSSSSEDSDTDESSSSSSSSASSTTSSSSSDSD 174

  Fly   156 GAPQKKKKRAGSSPESSDDQ 175
            .........:.|:..||||:
Human   175 SDSSSSSSSSTSTDSSSDDE 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5516	NP_001189228.1	zf-CCHC_3	27..59	CDD:290628	21/30 (70%)
ZCCHC10	NP_001295056.1	zf-CCHC_3	49..88	CDD:290628	23/34 (68%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159003
Domainoid	1	1.000	59	1.000	Domainoid score	I10711
eggNOG	1	0.900	-	-		E1_KOG3116
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	120	1.000	Inparanoid score	I4772
Isobase	1	0.950	-	0	Normalized mean entropy	S6420
OMA	1	1.010	-	-		QHG54889
OrthoDB	1	1.010	-	-		D1638633at2759
OrthoFinder	1	1.000	-	-		FOG0006615
OrthoInspector	1	1.000	-	-		oto91721
orthoMCL	1	0.900	-	-		OOG6_104907
Panther	1	1.100	-	-	LDO	PTHR13491
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5402
SonicParanoid	1	1.000	-	-		X5618
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	15	14.880