DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fbxl7 and AT5G27920

DIOPT Version :9

Sequence 1:	NP_650512.1	Gene:	Fbxl7 / 41935	FlyBaseID:	FBgn0038385	Length:	772	Species:	Drosophila melanogaster
Sequence 2:	NP_568502.1	Gene:	AT5G27920 / 832858	AraportID:	AT5G27920	Length:	642	Species:	Arabidopsis thaliana

Alignment Length:	366	Identity:	86/366 - (23%)
Similarity:	146/366 - (39%)	Gaps:	102/366 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   449 EHLNGDKTLKMIFRQLCGQSCNGACPEVERVMLADGCRISDKGLQLLTRRCPELTHLQLQTCVDI 513
            :::.|.|.||.|:                    .||..:||..|..|:..|..|..:.|..|||:
plant   294 KYIKGLKHLKTIW--------------------IDGAHVSDSSLVSLSSSCRSLMEIGLSRCVDV 338

  Fly   514 TNQALVEALTKCSNLQHLDVTGCSQVSSISPNPHMEPPRRLLLQYLDLTDCMAIDDMGLKIVVKN 578
            |:..::.....|.||:.|::..|..|:                            |:.:..|.::
plant   339 TDIGMISLARNCLNLKTLNLACCGFVT----------------------------DVAISAVAQS 375

  Fly   579 CPQLVYLYLRRCIQVTDAGLKFVPSFCVSLKELSVSDCLNITDFGLYELAKLGAALRYLSVAKCE 643
            |..|..|.|..|..:|:.||:.:..:.:.::||.::||..:.|.||..::|. :.|:.|.:..|.
plant   376 CRNLGTLKLESCHLITEKGLQSLGCYSMLVQELDLTDCYGVNDRGLEYISKC-SNLQRLKLGLCT 439

  Fly   644 RVSDAGLKVIARRCYKLRYLNARGCEAVSDDSITVLARSCPRLRALDIGKC-------------- 694
            .:||.|:..|..:|.||..|:...|....||.:..|:|.|..|..|.:..|
plant   440 NISDKGIFHIGSKCSKLLELDLYRCAGFGDDGLAALSRGCKSLNRLILSYCCELTDTGVEQIRQL 504

  Fly   695 ------------DVSDAGLRALAESCPNLKKLSLRSCDMITDRGVQCIAYYCRGLQQLNIQDCPV 747
                        :::..||.|:|..|..|..|.::.|:.|.|.|...:||:.:.|:|:|:.:|.|
plant   505 ELLSHLELRGLKNITGVGLAAIASGCKKLGYLDVKLCENIDDSGFWALAYFSKNLRQINLCNCSV 569

  Fly   748 S--------------------------IEGYR-AVKKYCKR 761
            |                          :||:. |::..|.|
plant   570 SDTALCMLMSNLSRVQDVDLVHLSRVTVEGFEFALRACCNR 610

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fbxl7	NP_650512.1	F-box-like	401..447	CDD:289689
		leucine-rich repeat	441..460	CDD:275381	4/10 (40%)
		AMN1	<451..595	CDD:187754	31/143 (22%)
		leucine-rich repeat	476..501	CDD:275381	7/24 (29%)
		leucine-rich repeat	502..521	CDD:275381	6/18 (33%)
		leucine-rich repeat	528..555	CDD:275381	4/26 (15%)
		leucine-rich repeat	556..581	CDD:275381	3/24 (13%)
		AMN1	577..746	CDD:187754	52/194 (27%)
		leucine-rich repeat	582..607	CDD:275381	7/24 (29%)
		leucine-rich repeat	608..633	CDD:275381	8/24 (33%)
		leucine-rich repeat	634..659	CDD:275381	8/24 (33%)
		leucine-rich repeat	660..685	CDD:275381	8/24 (33%)
		leucine-rich repeat	686..710	CDD:275381	8/49 (16%)
		leucine-rich repeat	711..735	CDD:275381	8/23 (35%)
		leucine-rich repeat	737..761	CDD:275381	10/50 (20%)
AT5G27920	NP_568502.1	AMN1	65..261	CDD:187754
		leucine-rich repeat	67..96	CDD:275381
		leucine-rich repeat	97..122	CDD:275381
		leucine-rich repeat	123..147	CDD:275381
		leucine-rich repeat	148..173	CDD:275381
		leucine-rich repeat	174..199	CDD:275381
		AMN1	192..393	CDD:187754	32/146 (22%)
		leucine-rich repeat	200..222	CDD:275381
		leucine-rich repeat	224..249	CDD:275381
		leucine-rich repeat	250..298	CDD:275381	0/3 (0%)
		leucine-rich repeat	299..352	CDD:275381	18/72 (25%)
		AMN1	<329..464	CDD:187754	40/163 (25%)
		leucine-rich repeat	353..378	CDD:275381	7/52 (13%)
		leucine-rich repeat	379..404	CDD:275381	7/24 (29%)
		AMN1	405..>567	CDD:187754	44/162 (27%)
		leucine-rich repeat	405..429	CDD:275381	8/24 (33%)
		leucine-rich repeat	430..455	CDD:275381	8/24 (33%)
		leucine-rich repeat	456..481	CDD:275381	8/24 (33%)
		leucine-rich repeat	482..506	CDD:275381	3/23 (13%)
		leucine-rich repeat	507..532	CDD:275381	5/24 (21%)
		leucine-rich repeat	533..558	CDD:275381	8/24 (33%)
		leucine-rich repeat	559..583	CDD:275381	6/23 (26%)
		leucine-rich repeat	584..609	CDD:275381	3/24 (13%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1195
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13318
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910