DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Fbxl7 and amn1

DIOPT Version :9

Sequence 1:	NP_650512.1	Gene:	Fbxl7 / 41935	FlyBaseID:	FBgn0038385	Length:	772	Species:	Drosophila melanogaster
Sequence 2:	NP_001038919.1	Gene:	amn1 / 751744	ZFINID:	ZDB-GENE-060825-13	Length:	249	Species:	Danio rerio

Alignment Length:	203	Identity:	59/203 - (29%)
Similarity:	100/203 - (49%)	Gaps:	25/203 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   553 RLLLQYLDLTDCMAIDDMGLKIVVKNCPQLVY-----LYLRRCIQVTDAGLKFVPSFCVSLKELS 612
            |::..|..:||             .|..|||:     |.|:.| :::|:.||.:.|  :.|:.:.
Zfish    38 RIMTSYGTVTD-------------SNISQLVHSGTHTLDLQNC-KISDSALKQINS--LHLRTIL 86

  Fly   613 VSDCLNITDFGLYELAKLGAALRYLSVAKCERVSDAGLKVIARRCYKLRYLNARGCEAVSDDSIT 677
            :..|..||..||..||.....|:.:.:..|..|:|:|::.:||.|..|..::.|||.|:||.::.
Zfish    87 LRGCAEITSEGLEVLAPRCPYLQVVDLTGCTAVTDSGIQALARHCKCLEVISLRGCSALSDKALL 151

  Fly   678 VLARSCPRLRALDIGKCDVSDAGLRALAE---SCPNLKKLSLRSCDMITDRGVQCIAYYCRGLQQ 739
            .|..:|..|.::.....:|:|.|:..||.   || :||:|.:..|..:||..|..:...|..::.
Zfish   152 ELGGNCKMLHSIYFSGTEVTDQGVIGLATGVCSC-SLKELQMVRCRNLTDLAVTAVLTNCANIRI 215

  Fly   740 LNIQDCPV 747
            .|...||:
Zfish   216 FNFHGCPL 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fbxl7	NP_650512.1	F-box-like	401..447	CDD:289689
		leucine-rich repeat	441..460	CDD:275381
		AMN1	<451..595	CDD:187754	11/46 (24%)
		leucine-rich repeat	476..501	CDD:275381
		leucine-rich repeat	502..521	CDD:275381
		leucine-rich repeat	528..555	CDD:275381	1/1 (100%)
		leucine-rich repeat	556..581	CDD:275381	4/24 (17%)
		AMN1	577..746	CDD:187754	53/176 (30%)
		leucine-rich repeat	582..607	CDD:275381	9/29 (31%)
		leucine-rich repeat	608..633	CDD:275381	8/24 (33%)
		leucine-rich repeat	634..659	CDD:275381	8/24 (33%)
		leucine-rich repeat	660..685	CDD:275381	9/24 (38%)
		leucine-rich repeat	686..710	CDD:275381	8/26 (31%)
		leucine-rich repeat	711..735	CDD:275381	7/23 (30%)
		leucine-rich repeat	737..761	CDD:275381	3/11 (27%)
amn1	NP_001038919.1	AMN1	33..248	CDD:187754	59/203 (29%)
		leucine-rich repeat	59..72	CDD:275381	3/13 (23%)
		leucine-rich repeat	82..107	CDD:275381	8/24 (33%)
		leucine-rich repeat	108..133	CDD:275381	8/24 (33%)
		leucine-rich repeat	134..159	CDD:275381	9/24 (38%)
		leucine-rich repeat	160..186	CDD:275381	8/26 (31%)
		leucine-rich repeat	187..212	CDD:275381	8/24 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810