Protein Alignment Fbxl7 and Fbxl7

DIOPT Version :10

• Sequence 1: NP_650512.1
• Gene: Fbxl7 / 41935
• FlyBaseID: FBgn0038385
• Length: 772
• Species: Drosophila melanogaster
• Sequence 2: NP_795933.2
• Gene: Fbxl7 / 448987
• MGIID: 3052506
• Length: 491
• Species: Mus musculus
• Alignment Length: 521
• Identity: 217/521 - (41%)
• Similarity: 319/521 - (61%)
• Gaps: 72/521 - (13%)

  Fly   282 SETSGSDRYLLNRSSNSNHLHSKGQSLSDGLCNLGRFSPSLDQGYATLVSPSP------------ 334
            ||..||.....:.||:::|..:|.|.      |:.. |...|....||.:|||
Mouse    11 SEGKGSSSVSSDVSSSTDHTPTKAQR------NVAT-SEDSDLSMRTLSTPSPALICPPTLPGFQ 68

  Fly   335 TGHHSSGGAGNVTNSTTASGAGIMASSTPTT-----------TPRRGASSNGLGGGAASAIGPPP 388
            .|..||..:.::|..|.|     |..|.|.|           .|::..:|
Mouse    69 NGRGSSTSSSSITGETVA-----MVHSPPPTRLTHPLIRLASRPQKEQAS--------------- 113

  Fly   389 WNRKGPFRCGPLFDRLPDEAVVRIFSWLDSCELCNVARVCRRFEHLAWRPILWKVISLRGEHLNG 453
                        .|||||.::|:|||:|.:.:||..||||||:.:|||.|.||:.|.|.||.:|.
Mouse   114 ------------IDRLPDHSMVQIFSFLPTNQLCRCARVCRRWYNLAWDPRLWRTIRLTGETINV 166

  Fly   454 DKTLKMIFRQLCGQSCNGACPEVERVMLADGC-RISDKGLQLLTRRCPELTHLQLQTCVDITNQA 517
            |:.||::.|:|| |.....|..:|.|::: || |::|:||..:.:.||||..|::..|.:|:|:|
Mouse   167 DRALKVLTRRLC-QDTPNVCLMLETVIVS-GCRRLTDRGLYTIAQCCPELRRLEVSGCYNISNEA 229

  Fly   518 LVEALTKCSNLQHLDVTGCSQVSSIS----PNPHMEP--PRRLLLQYLDLTDCMAIDDMGLKIVV 576
            :.:.::.|.||:||||:|||:|:.||    .:..:.|  .:::.::|||:|||..::|.||..:.
Mouse   230 VFDVVSLCPNLEHLDVSGCSKVTCISLTREASIKLSPLHGKQISIRYLDMTDCFVLEDEGLHTIA 294

  Fly   577 KNCPQLVYLYLRRCIQVTDAGLKFVPSFCVSLKELSVSDCLNITDFGLYELAKLGAALRYLSVAK 641
            .:|.||.:||||||:::||.||:::..:|.|:||||||||..::||||.|:|||.:.|||||:|.
Mouse   295 AHCTQLTHLYLRRCVRLTDEGLRYLVIYCTSIKELSVSDCRFVSDFGLREIAKLESRLRYLSIAH 359

  Fly   642 CERVSDAGLKVIARRCYKLRYLNARGCEAVSDDSITVLARSCPRLRALDIGKCD-VSDAGLRALA 705
            |.|::|.|::.:|:.|.|||||||||||.::|..:..||::|.:|::||||||. |||.||.:||
Mouse   360 CGRITDVGIRYVAKYCSKLRYLNARGCEGITDHGVEYLAKNCTKLKSLDIGKCPLVSDTGLESLA 424

  Fly   706 ESCPNLKKLSLRSCDMITDRGVQCIAYYCRGLQQLNIQDCPVSIEGYRAVKKYCKRCIIEHTNPG 770
            .:|.|||:|||:||:.||.:|:|.:|..|..||.||:|||.||:|..|.||::||||:||||||.
Mouse   425 LNCFNLKRLSLKSCESITGQGLQIVAANCFDLQMLNVQDCEVSVEALRFVKRHCKRCVIEHTNPA 489

  Fly   771 F 771
            |
Mouse   490 F 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fbxl7	NP_650512.1	leucine-rich repeat	502..521	CDD:275381	6/18 (33%)
		leucine-rich repeat	528..555	CDD:275381	12/32 (38%)
		leucine-rich repeat	556..581	CDD:275381	10/24 (42%)
		AMN1	577..746	CDD:187754	93/169 (55%)
		leucine-rich repeat	582..607	CDD:275381	12/24 (50%)
		leucine-rich repeat	608..633	CDD:275381	16/24 (67%)
		leucine-rich repeat	634..659	CDD:275381	12/24 (50%)
		leucine-rich repeat	660..685	CDD:275381	14/24 (58%)
		leucine-rich repeat	686..710	CDD:275381	15/24 (63%)
		leucine-rich repeat	711..735	CDD:275381	12/23 (52%)
		leucine-rich repeat	737..761	CDD:275381	14/23 (61%)
		dermokine	<279..>394	CDD:455732	29/134 (22%)
		F-box_SF	401..444	CDD:459239	24/42 (57%)
		leucine-rich repeat	441..460	CDD:275381	9/18 (50%)
		leucine-rich repeat	476..501	CDD:275381	9/25 (36%)
		LRR	<483..>640	CDD:443914	74/163 (45%)
Fbxl7	NP_795933.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..79		21/79 (27%)
		F-box_FBXL7	114..157	CDD:438892	14/42 (33%)
		leucine-rich repeat	129..151	CDD:275381	10/21 (48%)
		leucine-rich repeat	154..187	CDD:275381	18/32 (56%)
		AMN1	<185..366	CDD:187754	80/187 (43%)
		LRR 1	185..210		9/24 (38%)
		leucine-rich repeat	188..213	CDD:275381	7/24 (29%)
		LRR 2	211..236		11/25 (44%)
		leucine-rich repeat	214..234	CDD:275381	9/20 (45%)
		LRR 3	237..262		9/24 (38%)
		leucine-rich repeat	240..273	CDD:275381	16/36 (44%)
		LRR 4	271..296		9/30 (30%)
		leucine-rich repeat	274..299	CDD:275381	7/26 (27%)
		AMN1	297..464	CDD:187754	89/167 (53%)
		LRR 5	297..322		12/24 (50%)
		leucine-rich repeat	300..325	CDD:275381	12/24 (50%)
		LRR 6	323..348		14/24 (58%)
		leucine-rich repeat	326..351	CDD:275381	12/24 (50%)
		LRR 7	349..374		15/24 (63%)
		leucine-rich repeat	352..377	CDD:275381	14/24 (58%)
		LRR 8	375..400		15/24 (63%)
		leucine-rich repeat	378..403	CDD:275381	14/24 (58%)
		LRR 9	401..426		11/25 (44%)
		leucine-rich repeat	404..429	CDD:275381	13/25 (52%)
		LRR 10	427..452		14/24 (58%)
		leucine-rich repeat	430..453	CDD:275381	13/22 (59%)
		leucine-rich repeat	456..480	CDD:275381	12/23 (52%)