Protein Alignment Fbxl7 and fbxl2

DIOPT Version :9

• Sequence 1: NP_650512.1
• Gene: Fbxl7 / 41935
• FlyBaseID: FBgn0038385
• Length: 772
• Species: Drosophila melanogaster
• Sequence 2: NP_956400.1
• Gene: fbxl2 / 378737
• ZFINID: ZDB-GENE-030925-12
• Length: 432
• Species: Danio rerio
• Alignment Length: 443
• Identity: 128/443 - (28%)
• Similarity: 211/443 - (47%)
• Gaps: 87/443 - (19%)

  Fly   392 KGPFRC------GPLFDRLPDEAVVRIFSWLDSCELCNVARVCRRFEHLA-----WRPI------ 439
            ||.|..      .|:..:||.|.::||||:||...||..|:|.:.:..||     |:.|
Zfish     6 KGRFEVFSNNDEAPINKKLPKELLLRIFSYLDVVTLCRCAQVSKAWNVLALDGSNWQKIDLFNFQ 70

  Fly   440 -----------------LWKVISLRGEHLNGDKTLKMIFRQLCGQSCNGACPEVERVMLADGC-R 486
                             ..:.:||||....||.::|...:.         |..:|.:.| :|| :
Zfish    71 TDIEGRVVENISKRCGGFLRQLSLRGCLSVGDASMKTFAQN---------CRNIEHLNL-NGCTK 125

  Fly   487 ISDKGLQLLTRRCPELTHLQLQTCVDITNQALVEALTKCSNLQHLDVTGCSQVSSISPNPHMEPP 551
            |:|.....|::.|.:|.||.|.:||.|||.||......|..|::|:::.|.|::|    ..:|..
Zfish   126 ITDSTCISLSKFCFKLRHLDLTSCVSITNHALKALSEGCRMLENLNLSWCDQITS----DGIEAL 186

  Fly   552 RR--LLLQYLDLTDCMAIDDMGLKIVVKNCPQLVYLYLRRCIQVTDAGLKFVPSFCVSLKELSVS 614
            .|  ..|:.|.|..|..:||..||.:.|:||:|:.:.::.|.|:||.|...:...|..|:.:.:|
Zfish   187 SRGCTALRALFLRGCTQLDDTALKHLQKHCPELMTINMQSCTQITDDGFVSLCRGCHKLQMVCIS 251

  Fly   615 DCLNITDFGLYELAKLGAALRYLSVAKCERVSDAGLKVIARRCYKLRYLNARGCEAVSDDSITVL 679
            .|.||||..|..|......|:.|..|:|..|:|||..|:||.|:::..::...|..|:|:::..|
Zfish   252 GCSNITDASLTALGLNCQRLKILEAARCSHVTDAGFTVLARNCHEMEKMDLEECILVTDNTLVQL 316

  Fly   680 ARSCPRLRALDIGKCD-VSDAGLRALAES-C--PNLKKLSLRSCDMITDRGVQCIAYYCRGLQQL 740
            :..||||:||.:..|: ::|.|:|.|:.| |  ..|:.:.|.:|.:|||..::.:. .|:.|:::
Zfish   317 SIHCPRLQALSLSHCELITDDGIRHLSSSVCGQERLQVVELDNCPLITDITLEHLK-NCQRLERI 380

  Fly   741 NIQDC-----------------------------PVSIEGYRAVKKYCKRCII 764
            .:.||                             |.|:.|  ..::.|:.|:|
Zfish   381 ELYDCQQVSRAGIKRIRAHLPEIKVHAYFAPVTPPPSVHG--GGQRLCRCCVI 431

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fbxl7	NP_650512.1	F-box-like	401..447	CDD:289689	18/73 (25%)
		leucine-rich repeat	441..460	CDD:275381	7/18 (39%)
		AMN1	<451..595	CDD:187754	45/146 (31%)
		leucine-rich repeat	476..501	CDD:275381	8/25 (32%)
		leucine-rich repeat	502..521	CDD:275381	11/18 (61%)
		leucine-rich repeat	528..555	CDD:275381	7/28 (25%)
		leucine-rich repeat	556..581	CDD:275381	10/24 (42%)
		AMN1	577..746	CDD:187754	58/201 (29%)
		leucine-rich repeat	582..607	CDD:275381	7/24 (29%)
		leucine-rich repeat	608..633	CDD:275381	9/24 (38%)
		leucine-rich repeat	634..659	CDD:275381	12/24 (50%)
		leucine-rich repeat	660..685	CDD:275381	5/24 (21%)
		leucine-rich repeat	686..710	CDD:275381	10/27 (37%)
		leucine-rich repeat	711..735	CDD:275381	6/23 (26%)
		leucine-rich repeat	737..761	CDD:275381	7/52 (13%)
fbxl2	NP_956400.1	F-box-like	24..66	CDD:289689	17/41 (41%)
		leucine-rich repeat	61..88	CDD:275381	2/26 (8%)
		AMN1	63..284	CDD:187754	68/234 (29%)
		leucine-rich repeat	89..108	CDD:275381	7/18 (39%)
		leucine-rich repeat	115..140	CDD:275381	8/25 (32%)
		leucine-rich repeat	141..166	CDD:275381	12/24 (50%)
		leucine-rich repeat	167..192	CDD:275381	7/28 (25%)
		leucine-rich repeat	193..218	CDD:275381	10/24 (42%)
		AMN1	212..390	CDD:187754	58/178 (33%)
		leucine-rich repeat	219..244	CDD:275381	7/24 (29%)
		leucine-rich repeat	245..270	CDD:275381	9/24 (38%)
		leucine-rich repeat	271..296	CDD:275381	12/24 (50%)
		leucine-rich repeat	297..322	CDD:275381	5/24 (21%)
		leucine-rich repeat	323..351	CDD:275381	10/27 (37%)
		leucine-rich repeat	352..376	CDD:275381	7/24 (29%)
		leucine-rich repeat	377..402	CDD:275381	3/24 (13%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2139
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.940