DRSC/TRiP Functional Genomics Resources

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Protein Alignment Fbxl7 and Fbxl2

DIOPT Version :9

Sequence 1:NP_650512.1 Gene:Fbxl7 / 41935 FlyBaseID:FBgn0038385 Length:772 Species:Drosophila melanogaster
Sequence 2:XP_038938600.1 Gene:Fbxl2 / 363156 RGDID:1562243 Length:439 Species:Rattus norvegicus


Alignment Length:419 Identity:117/419 - (27%)
Similarity:196/419 - (46%) Gaps:83/419 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly   411 RIFSWLDSCELCNVARVCRRFEHLA-----WRPI-----------------------LWKVISLR 447
            ||||:||...||..|::.:.:..||     |:.:                       ..:.:|||
  Rat    38 RIFSFLDIVTLCRCAQISKAWNILALDGSNWQRVDLFNFQTDVEGRVVENISKRCGGFLRKLSLR 102

  Fly   448 GEHLNGDKTLKMIFRQLCGQSCNGACPEVERVMLADGC-RISDKGLQLLTRRCPELTHLQLQTCV 511
            |....||.:||...:.         |..:|.:.| :|| :|:|.....|:|.|.:|.||.|.:||
  Rat   103 GCIGVGDSSLKTFAQN---------CRNIEHLNL-NGCTKITDSTCYSLSRFCSKLKHLDLTSCV 157

  Fly   512 DITNQALVEALTKCSNLQHLDVTGCSQVSSISPNPHMEPPRRLL-----LQYLDLTDCMAIDDMG 571
            .:||.:|......|.||::|:::.|.|::.       |....|:     |:.|.|..|..::|..
  Rat   158 SVTNSSLKGISEGCRNLEYLNLSWCDQITK-------EGIEALVRGCRGLKALLLRGCTQLEDEA 215

  Fly   572 LKIVVKNCPQLVYLYLRRCIQVTDAGLKFVPSFCVSLKELSVSDCLNITDFGLYELAKLGAALRY 636
            ||.:..:|.:||.|.|:.|.::||.|:..:...|..|:.|.:|.|.|:||..|..|......|:.
  Rat   216 LKHIQNHCHELVSLNLQSCSRITDDGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQV 280

  Fly   637 LSVAKCERVSDAGLKVIARRCYKLRYLNARGCEAVSDDSITVLARSCPRLRALDIGKCD-VSDAG 700
            |..|:|..::|||..::||.|:.|..::...|..::|.::..|:..||:|:||.:..|: ::|.|
  Rat   281 LEAARCSHLTDAGFTLLARNCHDLEKMDLEECVLITDSTLIQLSIHCPKLQALSLSHCELITDEG 345

  Fly   701 LRALAES-C--PNLKKLSLRSCDMITDRGVQCIAYYCRGLQQLNIQDCP---------------- 746
            :..|:.| |  ..|:.|.|.:|.::||..::.:. .||||::|.:.||.                
  Rat   346 ILHLSSSTCGHERLRVLELDNCLLVTDASLEHLE-NCRGLERLELYDCQQVTRAGIKRMRAQLPR 409

  Fly   747 VSIEGYRAV-----------KKYCKRCII 764
            |.:..|.|.           .:.|:.|:|
  Rat   410 VKVHAYFAPVTPPPAVAGSGHRLCRCCVI 438

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Fbxl7NP_650512.1 F-box-like 401..447 CDD:289689 13/63 (21%)
leucine-rich repeat 441..460 CDD:275381 8/18 (44%)
AMN1 <451..595 CDD:187754 44/149 (30%)
leucine-rich repeat 476..501 CDD:275381 9/25 (36%)
leucine-rich repeat 502..521 CDD:275381 9/18 (50%)
leucine-rich repeat 528..555 CDD:275381 5/26 (19%)
leucine-rich repeat 556..581 CDD:275381 8/24 (33%)
AMN1 577..746 CDD:187754 56/172 (33%)
leucine-rich repeat 582..607 CDD:275381 9/24 (38%)
leucine-rich repeat 608..633 CDD:275381 9/24 (38%)
leucine-rich repeat 634..659 CDD:275381 10/24 (42%)
leucine-rich repeat 660..685 CDD:275381 5/24 (21%)
leucine-rich repeat 686..710 CDD:275381 9/27 (33%)
leucine-rich repeat 711..735 CDD:275381 6/23 (26%)
leucine-rich repeat 737..761 CDD:275381 8/50 (16%)
Fbxl2XP_038938600.1 F-box-like <38..72 CDD:403981 12/33 (36%)
leucine-rich repeat 68..95 CDD:275381 1/26 (4%)
AMN1 <92..239 CDD:187754 48/163 (29%)
leucine-rich repeat 96..115 CDD:275381 8/18 (44%)
leucine-rich repeat 122..147 CDD:275381 9/25 (36%)
leucine-rich repeat 148..173 CDD:275381 10/24 (42%)
leucine-rich repeat 174..199 CDD:275381 6/31 (19%)
AMN1 184..383 CDD:187754 61/206 (30%)
leucine-rich repeat 200..225 CDD:275381 8/24 (33%)
leucine-rich repeat 226..251 CDD:275381 9/24 (38%)
leucine-rich repeat 252..277 CDD:275381 9/24 (38%)
leucine-rich repeat 278..303 CDD:275381 10/24 (42%)
leucine-rich repeat 304..329 CDD:275381 5/24 (21%)
leucine-rich repeat 330..352 CDD:275381 7/21 (33%)
leucine-rich repeat 359..378 CDD:275381 6/18 (33%)
leucine-rich repeat 384..409 CDD:275381 4/24 (17%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.910

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