DRSC/TRiP Functional Genomics Resources

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Protein Alignment Fbxl7 and CG15056

DIOPT Version :9

Sequence 1:NP_650512.1 Gene:Fbxl7 / 41935 FlyBaseID:FBgn0038385 Length:772 Species:Drosophila melanogaster
Sequence 2:NP_573291.1 Gene:CG15056 / 32824 FlyBaseID:FBgn0030918 Length:399 Species:Drosophila melanogaster


Alignment Length:379 Identity:87/379 - (22%)
Similarity:148/379 - (39%) Gaps:81/379 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   413 FSWLDSCELCNV------ARVCRRFEHLAWR--PI-LWKVISLRGEHLNGDKTLKMIFRQLCGQS 468
            |.|||..:..::      |..|..||::..|  |: |.:|::|. |.:........:|.:|.|..
  Fly    14 FFWLDVLKQLDLKSRISFAASCDMFENIYVRSSPLRLSRVVNLE-EMIEFSLLETKLFVELSGSD 77

  Fly   469 CNGACPEVER-------------------VMLADGCRISDKGLQLLTRR---CPE-----LTHLQ 506
            .     |:.|                   :.|.....|:.:|.||...:   .||     ||::.
  Fly    78 I-----EIIRGGPHTPMFSHFEDFIRLMSIRLTKVNEIALEGFQLTQYKWFNAPETSFSNLTYVS 137

  Fly   507 LQTCVDITNQALV--EALT---------------KC-----SNLQHLDVTGCSQVSSISPNPHME 549
            |:.| .:.::.||  |.||               .|     ::|..|.:|||   .::.||..:.
  Fly   138 LRRC-QLNDENLVGWEFLTHLETLDLRYNDRLTGSCLMSLPTSLLSLYITGC---RNLCPNQLIF 198

  Fly   550 PPRRLLLQYLDLTDCMAIDDMGL-KIVVKNCPQLVYLYLRRCIQVTD----AGLKFVPSFCVSLK 609
            ..|...|:.|..:|.|......: :.:|..||.||.:.:..|....|    ..|:::.|..:...
  Fly   199 LNRIPRLRELRASDLMPGGHWHIYRDLVLACPLLVMVEISICSLNRDEYRLGELRYLQSLVIKAH 263

  Fly   610 ELSVSDCLNITDFGLYELAKLGAALRYL--SVAKCERVSDAGLKVIARRCYKLRYLNARGCEAVS 672
            ......| .::|:.|..|..: ..||.|  |.|....||...|.:|: |..:||.|.........
  Fly   264 STDTIRC-KVSDWMLISLLDV-PFLRNLMFSDAPSGFVSANALSIIS-RFRQLRVLKMPNQPYRP 325

  Fly   673 DDSITVLARSCPRLRALDIGKCD-VSDAGLRALAESCPNLKKLSLRSCDMITDR 725
            :|.:.:  |:...|..||:.... :::..:..|....|||..|.::.|.::|:|
  Fly   326 NDLLRL--RNLTFLETLDLSNSPYITNEVVIELVIGIPNLSVLIVQGCPLLTNR 377

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Fbxl7NP_650512.1 F-box-like 401..447 CDD:289689 12/42 (29%)
leucine-rich repeat 441..460 CDD:275381 3/18 (17%)
AMN1 <451..595 CDD:187754 40/193 (21%)
leucine-rich repeat 476..501 CDD:275381 6/46 (13%)
leucine-rich repeat 502..521 CDD:275381 6/20 (30%)
leucine-rich repeat 528..555 CDD:275381 8/26 (31%)
leucine-rich repeat 556..581 CDD:275381 6/25 (24%)
AMN1 577..746 CDD:187754 38/156 (24%)
leucine-rich repeat 582..607 CDD:275381 6/28 (21%)
leucine-rich repeat 608..633 CDD:275381 4/24 (17%)
leucine-rich repeat 634..659 CDD:275381 10/26 (38%)
leucine-rich repeat 660..685 CDD:275381 5/24 (21%)
leucine-rich repeat 686..710 CDD:275381 4/24 (17%)
leucine-rich repeat 711..735 CDD:275381 5/15 (33%)
leucine-rich repeat 737..761 CDD:275381
CG15056NP_573291.1 leucine-rich repeat 133..156 CDD:275381 8/23 (35%)
leucine-rich repeat 157..179 CDD:275381 1/21 (5%)
leucine-rich repeat 180..204 CDD:275381 8/26 (31%)
leucine-rich repeat 205..231 CDD:275381 6/25 (24%)
leucine-rich repeat 232..285 CDD:275381 10/54 (19%)
leucine-rich repeat 286..326 CDD:275381 13/40 (33%)
AMN1 306..>376 CDD:187754 16/72 (22%)
leucine-rich repeat 337..362 CDD:275381 4/24 (17%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45457925
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.830

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