DRSC/TRiP Functional Genomics Resources

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Protein Alignment Fbxl7 and fbxl14b

DIOPT Version :9

Sequence 1:NP_650512.1 Gene:Fbxl7 / 41935 FlyBaseID:FBgn0038385 Length:772 Species:Drosophila melanogaster
Sequence 2:NP_001015043.1 Gene:fbxl14b / 324835 ZFINID:ZDB-GENE-030131-3556 Length:400 Species:Danio rerio


Alignment Length:397 Identity:98/397 - (24%)
Similarity:176/397 - (44%) Gaps:83/397 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   407 EAVVRIFSWLDSCELCNVARVCRRFEHLAWRPILWK----------------------------V 443
            |.:..|||:||..:...||:||..:...::...:|:                            :
Zfish    11 EILAMIFSYLDVRDKGRVAQVCTAWRDASYHKSVWRGVEAKLHLRRANPSLFPSLQARGIRRVQI 75

  Fly   444 ISLRGEHLNGDKTLKMIFRQLCGQSCNGACPEVERVMLADGC-RISDKGL-QLLTRRCPELTHLQ 506
            :|||       ::|..:.:.:         |.:|.:.|: || .::|.|| ....:..|.|..|.
Zfish    76 LSLR-------RSLSYVIQGM---------PNIESLNLS-GCYNLTDNGLGHAFVQEIPSLRVLN 123

  Fly   507 LQTCVDITNQALVEALTKCSNLQHLDVTGCSQVSS-----ISPNPHMEPPRRLLLQYLDLTDCMA 566
            |..|..||:.:|........||:.|::.|||.:::     |:...|.       |:.|:|..|..
Zfish   124 LSLCKQITDSSLGRIAQYLKNLEVLELGGCSNITNTGLLLIAWGLHR-------LKSLNLRSCRH 181

  Fly   567 IDDMGL-------KIVVKNCPQLVYLYLRRCIQVTDAGLKFVPSFCVSLKELSVSDCLNITDFGL 624
            :.|:|:       :...:.|..|.||.|:.|.::||..||.:......||.|::|.|..|:|.|:
Zfish   182 VSDVGIGHLAGMTRSAAEGCLSLEYLTLQDCQKLTDLSLKHISKGLTKLKVLNLSFCGGISDAGM 246

  Fly   625 YELAKLGAALRYLSVAKCERVSDAGLKVIARRCYKLRYLNARGCEAVSDDSITVLARSCPRLRAL 689
            ..|:.: .:|..|::..|:.:||.|:..:|....:|..|:...|:.:.|.|:..:|:...:|::|
Zfish   247 IHLSHM-TSLWSLNLRSCDNISDTGIMHLAMGTLRLSGLDVSFCDKIGDQSLAYIAQGLYQLKSL 310

  Fly   690 DIGKCDVSDAGLRALAESCPNLKKLSLRSCDMITDRGVQCIA-----------YYC-----RGLQ 738
            .:..|.:||.|:..:......|:.|::..|..|||:|::.||           |.|     |||:
Zfish   311 SLCSCHISDDGINRMVRQMHELRTLNIGQCVRITDKGLELIADHLTQLTGIDLYGCTKITKRGLE 375

  Fly   739 QLNIQDC 745
            ::....|
Zfish   376 RITQLPC 382

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Fbxl7NP_650512.1 F-box-like 401..447 CDD:289689 12/67 (18%)
leucine-rich repeat 441..460 CDD:275381 5/46 (11%)
AMN1 <451..595 CDD:187754 37/157 (24%)
leucine-rich repeat 476..501 CDD:275381 7/26 (27%)
leucine-rich repeat 502..521 CDD:275381 7/18 (39%)
leucine-rich repeat 528..555 CDD:275381 7/31 (23%)
leucine-rich repeat 556..581 CDD:275381 7/31 (23%)
AMN1 577..746 CDD:187754 53/185 (29%)
leucine-rich repeat 582..607 CDD:275381 9/24 (38%)
leucine-rich repeat 608..633 CDD:275381 9/24 (38%)
leucine-rich repeat 634..659 CDD:275381 7/24 (29%)
leucine-rich repeat 660..685 CDD:275381 6/24 (25%)
leucine-rich repeat 686..710 CDD:275381 6/23 (26%)
leucine-rich repeat 711..735 CDD:275381 11/39 (28%)
leucine-rich repeat 737..761 CDD:275381 2/9 (22%)
fbxl14bNP_001015043.1 F-box-like 5..46 CDD:403981 10/34 (29%)
AMN1 90..296 CDD:187754 60/214 (28%)
leucine-rich repeat 92..118 CDD:275381 7/26 (27%)
leucine-rich repeat 119..144 CDD:275381 7/24 (29%)
leucine-rich repeat 145..170 CDD:275381 6/24 (25%)
leucine-rich repeat 171..203 CDD:275381 7/31 (23%)
leucine-rich repeat 204..229 CDD:275381 9/24 (38%)
AMN1 230..388 CDD:187754 43/154 (28%)
leucine-rich repeat 230..254 CDD:275381 9/24 (38%)
leucine-rich repeat 255..280 CDD:275381 7/24 (29%)
leucine-rich repeat 281..304 CDD:275381 6/22 (27%)
leucine-rich repeat 307..331 CDD:275381 6/23 (26%)
leucine-rich repeat 332..357 CDD:275381 9/24 (38%)
leucine-rich repeat 358..382 CDD:275381 5/23 (22%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

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