Protein Alignment Fbxl7 and Fbxl16

DIOPT Version :9

• Sequence 1: NP_650512.1
• Gene: Fbxl7 / 41935
• FlyBaseID: FBgn0038385
• Length: 772
• Species: Drosophila melanogaster
• Sequence 2: NP_001366323.1
• Gene: Fbxl16 / 214931
• MGIID: 2448488
• Length: 575
• Species: Mus musculus
• Alignment Length: 524
• Identity: 128/524 - (24%)
• Similarity: 206/524 - (39%)
• Gaps: 127/524 - (24%)

  Fly   319 SPSLDQGYATLVSPSP-----------TGHHSSGGAGNVTNSTTASGAGIMASSTPTTTP----- 367
            ||.:|.      .|.|           .|..:..||.::|..|.|:.........|.|.|
Mouse    99 SPGIDG------DPKPPCLPRNGLVKLPGQPNGLGAASITKGTPAAKNRPCQPPPPPTLPPPSLA 157

  Fly   368 ---RRGASSNGLGGGAASAIGPPPWNRKGPFRCGPLFDRLP---DEAVVR-IFSWLDSCELCNVA 425
               .|.|.:   ||....|.||    ..||. .||..:|.|   ||.::. :|.:..:||.|.:|
Mouse   158 TPLSRVALA---GGPCPPASGP----ASGPV-SGPPVERPPLATDEKILNGLFWYFSACEKCILA 214

  Fly   426 RVCRRFEHLAWRPILWKVIS--LRGEHL-----NGDKTLKMI-------FRQLC--GQSCNGACP 474
            :||:.:..:.::|..|..::  |..:.|     .|:|....:       |...|  |.|....|.
Mouse   215 QVCKAWRRVLYQPKFWAGLTPVLHAKELYNVLPGGEKEFVNLQGFAARGFEGFCLVGVSDLDICE 279

  Fly   475 EVERVMLA-DGCR--------ISDKGLQLLTRRCPELTHLQLQTCVDITNQALVEALTKCSNLQH 530
            .::...|: .|.:        |:|.||:::..:...:..|:|..|.|.|...|..:|:  :.:..
Mouse   280 FIDNYSLSKKGVKAMSLKRSTITDAGLEVMLEQMQGVVRLELSGCNDFTEAGLWSSLS--ARITS 342

  Fly   531 LDVTGC--------SQVSSISPNPHMEPPRRLLLQYLDLTD---------------------CMA 566
            |.|:.|        :.:|.:.||     ...|.||...:||                     |..
Mouse   343 LSVSDCINVADDAIAAISQLLPN-----LAELSLQAYHVTDTALAYFTARQGHSTHTLRLLSCWE 402

  Fly   567 IDDMGLKIVVKNCPQLVYLYLRRCIQVTDAGLKFVPSFCVSLKELSVSDCLNITDFGLYELAKLG 631
            |.:.|:..||.:.|.|..|.|..|.:|||.|::.|......|:.|.:|.|..|||..|..:|...
Mouse   403 ITNHGVVNVVHSLPNLTSLSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMALEYVACDL 467

  Fly   632 AALRYLSVAKCERVSDAGLKVIARRCYKLRYLNARGCEAVSDDSITVLARSCPRLRALDIGKCDV 696
            ..|..|.:.:|.|::|.||..::... .||.|..|.|                         |.|
Mouse   468 HRLEELVLDRCVRITDTGLSYLSTMS-SLRSLYLRWC-------------------------CQV 506

  Fly   697 SDAGLRALAESCPNLKKLSLRSCDMITDRGVQCIAYYCRGLQQLNIQDCP-VSIEGYRAVKKYCK 760
            .|.||:.|. :..||:.|||..|.::|..|:..:. ..:.|::|.:.:|| .:.|.::...::..
Mouse   507 QDFGLKHLL-AMRNLRLLSLAGCPLLTTTGLSGLV-QLQELEELELTNCPGATPELFKYFSQHLP 569

  Fly   761 RCII 764
            ||::
Mouse   570 RCLV 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fbxl7	NP_650512.1	F-box-like	401..447	CDD:289689	13/51 (25%)
		leucine-rich repeat	441..460	CDD:275381	5/25 (20%)
		AMN1	<451..595	CDD:187754	43/195 (22%)
		leucine-rich repeat	476..501	CDD:275381	6/33 (18%)
		leucine-rich repeat	502..521	CDD:275381	6/18 (33%)
		leucine-rich repeat	528..555	CDD:275381	6/34 (18%)
		leucine-rich repeat	556..581	CDD:275381	9/45 (20%)
		AMN1	577..746	CDD:187754	47/168 (28%)
		leucine-rich repeat	582..607	CDD:275381	9/24 (38%)
		leucine-rich repeat	608..633	CDD:275381	9/24 (38%)
		leucine-rich repeat	634..659	CDD:275381	7/24 (29%)
		leucine-rich repeat	660..685	CDD:275381	5/24 (21%)
		leucine-rich repeat	686..710	CDD:275381	6/23 (26%)
		leucine-rich repeat	711..735	CDD:275381	7/23 (30%)
		leucine-rich repeat	737..761	CDD:275381	5/24 (21%)
Fbxl16	NP_001366323.1	PHA03247	<31..193	CDD:223021	27/107 (25%)
		AMN1	297..509	CDD:187754	60/244 (25%)
		leucine-rich repeat	316..339	CDD:275381	7/24 (29%)
		leucine-rich repeat	340..365	CDD:275381	4/24 (17%)
		leucine-rich repeat	366..391	CDD:275381	5/24 (21%)
		leucine-rich repeat	392..417	CDD:275381	5/24 (21%)
		leucine-rich repeat	418..443	CDD:275381	9/24 (38%)
		leucine-rich repeat	444..469	CDD:275381	9/24 (38%)
		leucine-rich repeat	470..494	CDD:275381	7/24 (29%)
		leucine-rich repeat	495..514	CDD:275381	10/43 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810