DRSC/TRiP Functional Genomics Resources

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Protein Alignment Fbxl7 and AMN1

DIOPT Version :9

Sequence 1:NP_650512.1 Gene:Fbxl7 / 41935 FlyBaseID:FBgn0038385 Length:772 Species:Drosophila melanogaster
Sequence 2:NP_001106873.1 Gene:AMN1 / 196394 HGNCID:27281 Length:258 Species:Homo sapiens


Alignment Length:223 Identity:67/223 - (30%)
Similarity:99/223 - (44%) Gaps:42/223 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   540 SSISPNPHMEPPRRLLLQYLDLTDCMAIDDMGLKIVVKNCPQLVYLYLRRC----IQVTDAGLKF 600
            |:||...|.|      :|.|||..| .|.|..| :.:.||.:|..|.|...    :.||..|:|.
Human    53 SNISEILHPE------VQTLDLRSC-DISDAAL-LHLSNCRKLKKLNLNASKGNRVSVTSEGIKA 109

  Fly   601 VPSFCVSLKELSVSDCLNITDFGLYELAKLGAALRYLSVAKCERVSDAGLKVIARRCYKLRYLNA 665
            |.|.|..|.|.|:..|.|:|                          |.|:..:|..|..|:.::.
Human   110 VASSCSYLHEASLKRCCNLT--------------------------DEGVVALALNCQLLKIIDL 148

  Fly   666 RGCEAVSDDSITVLARSCPRLRALDIGKCDVSDAGLRALAESCPNLKKLS---LRSCDMITDRGV 727
            .||.:::|.|:..|.::||.|:.:|.....|||:|:.||. |.|..|||.   :..|..:||..|
Human   149 GGCLSITDVSLHALGKNCPFLQCVDFSATQVSDSGVIALV-SGPCAKKLEEIHMGHCVNLTDGAV 212

  Fly   728 QCIAYYCRGLQQLNIQDCPVSIEGYRAV 755
            :.:..||..::.|....||:..:..|.|
Human   213 EAVLTYCPQIRILLFHGCPLITDHSREV 240

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Fbxl7NP_650512.1 F-box-like 401..447 CDD:289689
leucine-rich repeat 441..460 CDD:275381
AMN1 <451..595 CDD:187754 19/58 (33%)
leucine-rich repeat 476..501 CDD:275381
leucine-rich repeat 502..521 CDD:275381
leucine-rich repeat 528..555 CDD:275381 5/14 (36%)
leucine-rich repeat 556..581 CDD:275381 10/24 (42%)
AMN1 577..746 CDD:187754 50/175 (29%)
leucine-rich repeat 582..607 CDD:275381 10/28 (36%)
leucine-rich repeat 608..633 CDD:275381 6/24 (25%)
leucine-rich repeat 634..659 CDD:275381 4/24 (17%)
leucine-rich repeat 660..685 CDD:275381 7/24 (29%)
leucine-rich repeat 686..710 CDD:275381 9/23 (39%)
leucine-rich repeat 711..735 CDD:275381 8/26 (31%)
leucine-rich repeat 737..761 CDD:275381 5/19 (26%)
AMN1NP_001106873.1 AMN1 37..257 CDD:187754 67/223 (30%)
leucine-rich repeat 63..86 CDD:275381 10/24 (42%)
leucine-rich repeat 87..116 CDD:275381 10/28 (36%)
leucine-rich repeat 117..142 CDD:275381 10/50 (20%)
leucine-rich repeat 143..168 CDD:275381 7/24 (29%)
leucine-rich repeat 169..195 CDD:275381 10/26 (38%)
leucine-rich repeat 196..221 CDD:275381 7/24 (29%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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