DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fbxl7 and zeel-1

DIOPT Version :9

Sequence 1:	NP_650512.1	Gene:	Fbxl7 / 41935	FlyBaseID:	FBgn0038385	Length:	772	Species:	Drosophila melanogaster
Sequence 2:	NP_490966.2	Gene:	zeel-1 / 189770	WormBaseID:	WBGene00021463	Length:	917	Species:	Caenorhabditis elegans

Alignment Length:	213	Identity:	43/213 - (20%)
Similarity:	83/213 - (38%)	Gaps:	44/213 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   522 LTKCS---NLQHLDVTGCSQVSSISPNPHMEPPRRLLLQYLDLTDCMAIDDMGLKIVVKNCPQLV 583
            |..|:   .|.|...:..:.:::.....|:...|......|:..|....|.:..|:::.| |: .
Worm   208 LNHCNTAYRLPHKMTSSLANITAAQIARHINDGRYTRTNILEGMDTKFRDTILSKLLLLN-PK-A 270

  Fly   584 YLYLRRCIQVTDAGLKFVPSFCVSLKELSVSDCLNITDFGLYELAKLGAALRYLSVAKCERVSDA 648
            |.::.:..||.              |.||:...:    |.|...|:..:.:..|::
Worm   271 YQFIAKTTQVE--------------KSLSIGKRV----FELEYYARHKSIITTLTI--------- 308

  Fly   649 GLKVIARRCY--KLRYLNARGCEA-VSDDSITVLARSCPRLRALDIGKCDVSDAGLRALAESCPN 710
               |:.::.|  |::.|:.|.||| ::...:..:......|..|:|....:|......|.:|.||
Worm   309 ---VLHKKKYWEKIQKLDIRECEAQLTPGWVKQIGIMLSSLTTLEISNKPLSKEDFSELCDSFPN 370

  Fly   711 LKKLSLRSCDMITDRGVQ 728
            |.:|.      |:|.|::
Worm   371 LVQLD------ISDTGIR 382

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fbxl7	NP_650512.1	F-box-like	401..447	CDD:289689
		leucine-rich repeat	441..460	CDD:275381
		AMN1	<451..595	CDD:187754	15/75 (20%)
		leucine-rich repeat	476..501	CDD:275381
		leucine-rich repeat	502..521	CDD:275381
		leucine-rich repeat	528..555	CDD:275381	4/26 (15%)
		leucine-rich repeat	556..581	CDD:275381	5/24 (21%)
		AMN1	577..746	CDD:187754	33/155 (21%)
		leucine-rich repeat	582..607	CDD:275381	3/24 (13%)
		leucine-rich repeat	608..633	CDD:275381	6/24 (25%)
		leucine-rich repeat	634..659	CDD:275381	3/26 (12%)
		leucine-rich repeat	660..685	CDD:275381	5/25 (20%)
		leucine-rich repeat	686..710	CDD:275381	6/23 (26%)
		leucine-rich repeat	711..735	CDD:275381	5/18 (28%)
		leucine-rich repeat	737..761	CDD:275381
zeel-1	NP_490966.2	leucine-rich repeat	346..370	CDD:275380	6/23 (26%)
		leucine-rich repeat	371..392	CDD:275380	5/18 (28%)
		leucine-rich repeat	393..417	CDD:275380
		leucine-rich repeat	418..447	CDD:275380
		leucine-rich repeat	448..471	CDD:275380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162679
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930