DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fbxl7 and K02A6.3

DIOPT Version :9

Sequence 1:	NP_650512.1	Gene:	Fbxl7 / 41935	FlyBaseID:	FBgn0038385	Length:	772	Species:	Drosophila melanogaster
Sequence 2:	NP_001024745.1	Gene:	K02A6.3 / 181077	WormBaseID:	WBGene00019294	Length:	483	Species:	Caenorhabditis elegans

Alignment Length:	283	Identity:	57/283 - (20%)
Similarity:	99/283 - (34%)	Gaps:	82/283 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   450 HLNGDKTLKMIFRQLCGQSCNGACPEVERVMLADGCRISDKGLQLLTRRCPELTHLQLQT----- 509
            :|:|.|:|.::..||.....:                  |....||.:...:||:|.|..
Worm   170 YLHGLKSLSLVDLQLTHDEAD------------------DFLSTLLEKFYEKLTYLSLLNVTLYP 216

  Fly   510 -------CVDITNQALV-------EALTKCSNLQHLDVTGCSQVSSISPNPH-MEPPRRLLLQYL 559
                   |.....:.||       :.|:..:.|:||:.....||::   .|: :.||........
Worm   217 KPLLQVGCFLKLRKLLVSPQMLSTDTLSAIACLEHLETLSIVQVTA---TPYSLFPPTSSATDSF 278

  Fly   560 DLTD---------CMAIDDMGLKIVVKNCPQL-VYLYLR---RCIQVTDAGLKFVPSFCVSLK-- 609
            ...|         |....||.:|   :|..:. |:|.||   :...:...|   .|.:.:.::
Worm   279 VFQDEKSSQSTDICRNAWDMFVK---QNMDRTRVWLILRGKPKMSLIIQPG---APIYGIKMENS 337

  Fly   610 --ELSVSDCLNITDFGLYELAKLGAALRYLSVAKCERVS---------DAGLKVIARRCYKLRYL 663
              :|::.....|.::       .||.||:......||:.         |:.|..|..||..|..|
Worm   338 AGQLTMELAEQIANY-------YGATLRHFIQCGLERMKRGKKMEERVDSALIEIVSRCPNLERL 395

  Fly   664 NARGCEAVSDDSITVLARSCPRL 686
            ..|  |.:|..:..:|:....|:
Worm   396 ACR--ERMSYGTAVILSVYAERI 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fbxl7	NP_650512.1	F-box-like	401..447	CDD:289689
		leucine-rich repeat	441..460	CDD:275381	4/9 (44%)
		AMN1	<451..595	CDD:187754	35/176 (20%)
		leucine-rich repeat	476..501	CDD:275381	3/24 (13%)
		leucine-rich repeat	502..521	CDD:275381	7/37 (19%)
		leucine-rich repeat	528..555	CDD:275381	8/27 (30%)
		leucine-rich repeat	556..581	CDD:275381	6/33 (18%)
		AMN1	577..746	CDD:187754	27/127 (21%)
		leucine-rich repeat	582..607	CDD:275381	6/28 (21%)
		leucine-rich repeat	608..633	CDD:275381	3/28 (11%)
		leucine-rich repeat	634..659	CDD:275381	9/33 (27%)
		leucine-rich repeat	660..685	CDD:275381	6/24 (25%)
		leucine-rich repeat	686..710	CDD:275381	0/1 (0%)
		leucine-rich repeat	711..735	CDD:275381
		leucine-rich repeat	737..761	CDD:275381
K02A6.3	NP_001024745.1	FBOX	10..50	CDD:197608
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910