DRSC/TRiP Functional Genomics Resources

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Protein Alignment Fbxl7 and FBXO39

DIOPT Version :9

Sequence 1:NP_650512.1 Gene:Fbxl7 / 41935 FlyBaseID:FBgn0038385 Length:772 Species:Drosophila melanogaster
Sequence 2:NP_694962.1 Gene:FBXO39 / 162517 HGNCID:28565 Length:442 Species:Homo sapiens


Alignment Length:367 Identity:74/367 - (20%)
Similarity:122/367 - (33%) Gaps:120/367 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   404 LPDEAVVRIFSWLDSCELCNVARVCRRFEHLAWRPILWKVISLRGEHLNGDKTLKMIFRQLCGQS 468
            |||..:.|:|.||...:....|.|||::..:.:...||:..::                ...|:.
Human    19 LPDLCLCRVFWWLGDRDRSRAALVCRKWNQMMYSAELWRYRTI----------------TFSGRP 67

  Fly   469 CNGACPEVERVMLADGCRISDKGLQLLTRRCPELTHLQ----------LQTCVDITNQALVEALT 523
            ......|||            ..:..:.:....|.||:          |.....:|.:.|:..|:
Human    68 SRVHASEVE------------SAVWYVKKFGRYLEHLEVKFMNPYNAVLTKKFQVTMRGLLSCLS 120

  Fly   524 KCSNLQHLDVTGCSQVSSISPNPHMEPPRRLLLQYLDLTDCMAIDDM------GLKIVVKNC-PQ 581
            |.:|          ::.|:|            :|||:|...:..:.:      .|...:|.. .:
Human   121 KSNN----------RLKSLS------------IQYLELDRLVWRNSIRSSFISSLSFFLKKMGKR 163

  Fly   582 LVYLYLRRCIQVTDAGLKFVPSFCVSLKELSVSDCLNITDFGLYELAKLGAALRYLSVAKCERVS 646
            |.||.|:......:.|.:.:.|......|..:|: |||.|:..:.||.               .:
Human   164 LDYLNLKGARLTVEQGCQILDSLSYMRNENVISE-LNIEDYFSHHLAV---------------YN 212

  Fly   647 DAGLKVIARRCYKLRYLNAR-GCEAVSDDSITVLARSCPRLRALDIGKCDVSDA------GL--R 702
            ....|......:.|..||.. .|  :||:.:..|..:...||.::| ||.|.|.      |:  .
Human   213 SPQFKKTMSTFHNLVSLNLNYNC--ISDELLENLCENASTLRTINI-KCHVHDPHGQVIWGMSWA 274

  Fly   703 ALAESCPNLK-------------------------KLSLRSC 719
            .||....|||                         .:|||||
Human   275 KLARQATNLKVNFFFERIMKYERLARILLQEIPIRSISLRSC 316

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Fbxl7NP_650512.1 F-box-like 401..447 CDD:289689 13/42 (31%)
leucine-rich repeat 441..460 CDD:275381 1/18 (6%)
AMN1 <451..595 CDD:187754 25/160 (16%)
leucine-rich repeat 476..501 CDD:275381 2/24 (8%)
leucine-rich repeat 502..521 CDD:275381 6/28 (21%)
leucine-rich repeat 528..555 CDD:275381 2/26 (8%)
leucine-rich repeat 556..581 CDD:275381 6/31 (19%)
AMN1 577..746 CDD:187754 41/178 (23%)
leucine-rich repeat 582..607 CDD:275381 6/24 (25%)
leucine-rich repeat 608..633 CDD:275381 8/24 (33%)
leucine-rich repeat 634..659 CDD:275381 1/24 (4%)
leucine-rich repeat 660..685 CDD:275381 7/25 (28%)
leucine-rich repeat 686..710 CDD:275381 10/31 (32%)
leucine-rich repeat 711..735 CDD:275381 7/34 (21%)
leucine-rich repeat 737..761 CDD:275381
FBXO39NP_694962.1 F-box-like 16..57 CDD:289689 12/37 (32%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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