DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment EndoU and Endou

DIOPT Version :9

Sequence 1:	NP_650508.1	Gene:	EndoU / 41931	FlyBaseID:	FBgn0038381	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	NP_001177998.1	Gene:	Endou / 680317	RGDID:	1593011	Length:	411	Species:	Rattus norvegicus

Alignment Length:	286	Identity:	93/286 - (32%)
Similarity:	144/286 - (50%)	Gaps:	29/286 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 TPDDVLTLSKNLY------AEETEVSPYLYKVNLQGKTTSGAHDDRAPRNLFE-LHQDLLARDAN 110
            |.:::.::|:.:|      |::.::  .|...|......:|...||.|..||: :::.|.::
  Rat   137 TKEELKSISETIYRVDINKAQKKDI--VLNSQNQISPAETGNQVDRCPEPLFKYVNEKLFSK--- 196

  Fly   111 STTALLMRLFDNYELDVAVQEHPTPEHVQEQYDFLRAVMGTRVMKLTMRFLVHKDIVSVEYDDQL 175
            .|.|..:.|.:||:......||.:.:.::||..|||.||.|.|||....||.|::    .|..|.
  Rat   197 PTYAAFINLLNNYQRATGHGEHFSAQQLEEQVVFLREVMKTAVMKELYSFLRHQN----RYGSQQ 257

  Fly   176 RLLQEL---WFTPYSRGRGIVGSSSFEHVFMAEIRDQKVLGLHNWLYFADQEQRGNVDYKGWLNH 237
            ..:::|   ||..||||.....||.|||||..|::..||.|.|||:.|..||:.|.:||   .:|
  Rat   258 EFVEDLKNMWFGLYSRGNEEGDSSGFEHVFSGEVKKGKVTGFHNWIRFYLQEKEGLLDY---YSH 319

  Fly   238 KEMGKHNQM--VLSVRYTFHNINKPVNGFFVGISPELDMALYTACFLATAKEEPCHIQLGHASAT 300
            ...|..:..  ||::::.:....|.|...|:|.|||.:.|||:.||: |...:.||:.||.....
  Rat   320 NYDGPWDSYPDVLAMQFNWDGYYKEVGSVFIGSSPEFEFALYSLCFI-TRPGKKCHLSLGGYPLA 383

  Fly   301 IVSHEWK----WNGMRLIGTVYPDSS 322
            |.::.|.    .||.:.|.|.|..||
  Rat   384 IQTYTWDKTTYGNGKKYIATAYVVSS 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
EndoU	NP_650508.1	XendoU	55..319	CDD:286496	89/279 (32%)
Endou	NP_001177998.1	Somatomedin_B	22..60	CDD:279385
		Somatomedin_B	88..125	CDD:279385
		XendoU	139..405	CDD:286496	89/278 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352172
Domainoid	1	1.000	161	1.000	Domainoid score	I3916
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	131	1.000	Inparanoid score	I4541
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D596408at33208
OrthoFinder	1	1.000	-	-		FOG0003014
OrthoInspector	1	1.000	-	-		otm45493
orthoMCL	1	0.900	-	-		OOG6_102937
Panther	1	1.100	-	-	O	PTHR12439
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.900