DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment EndoU and Endou

DIOPT Version :9

Sequence 1:	NP_650508.1	Gene:	EndoU / 41931	FlyBaseID:	FBgn0038381	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	NP_032928.1	Gene:	Endou / 19011	MGIID:	97746	Length:	454	Species:	Mus musculus

Alignment Length:	284	Identity:	95/284 - (33%)
Similarity:	144/284 - (50%)	Gaps:	25/284 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 TPDDVLTLSKNLYAEETEVSP----YLYKVNLQGKTTSGAHDDRAPRNLFE-LHQDLLARDANST 112
            |.:::.::|:.:|..:|..:.    .|...|....:.:|...||:|..||. :::.|.::   .|
Mouse   180 TKEELESISETIYRVDTNKAQKEDIVLNSQNRISPSETGNQVDRSPEPLFTYVNEKLFSK---PT 241

  Fly   113 TALLMRLFDNYELDVAVQEHPTPEHVQEQYDFLRAVMGTRVMKLTMRFLVHKDIVSVE---YDDQ 174
            .|..:.|.:||:......||.:.:.::||..|||.||.|.|||....||.|::..|.|   .||
Mouse   242 YAAFINLLNNYQRATGHGEHFSAQQLEEQGVFLREVMKTAVMKELYSFLHHQNRYSSEQEFVDD- 305

  Fly   175 LRLLQELWFTPYSRGRGIVGSSSFEHVFMAEIRDQKVLGLHNWLYFADQEQRGNVDYKGWLNHKE 239
               |:.:||..||||.....||.|||||..|::..||.|.|||:.|..||:.|.:||   .:|..
Mouse   306 ---LKNMWFGLYSRGNDEGDSSGFEHVFSGEVKKGKVTGFHNWIRFYLQEKEGLLDY---YSHNY 364

  Fly   240 MGKHNQM--VLSVRYTFHNINKPVNGFFVGISPELDMALYTACFLATAKEEPCHIQLGHASATIV 302
            .|..:..  ||::::.:....|.|...|:|.|||.:.|||:.||: |...:.||:.||.....|.
Mouse   365 DGPWDSYPDVLAMQFNWDGYYKEVGSVFIGSSPEFEFALYSLCFI-TRPGKKCHLSLGGYPLAIQ 428

  Fly   303 SHEWK----WNGMRLIGTVYPDSS 322
            ::.|.    .||.:.|.|.|..||
Mouse   429 TYTWDKTTYGNGKKYIATAYVVSS 452

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
EndoU	NP_650508.1	XendoU	55..319	CDD:286496	91/277 (33%)
Endou	NP_032928.1	Somatomedin_B	130..167	CDD:279385
Endou	NP_032928.1	XendoU	182..448	CDD:286496	91/276 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167848574
Domainoid	1	1.000	168	1.000	Domainoid score	I3819
eggNOG	1	0.900	-	-		E1_KOG2849
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I4575
Isobase	1	0.950	-	0.815465	Normalized mean entropy	S5851
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003014
OrthoInspector	1	1.000	-	-		otm43429
orthoMCL	1	0.900	-	-		OOG6_102937
Panther	1	1.100	-	-	O	PTHR12439
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.700