DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14877 and adcy2a

DIOPT Version :9

Sequence 1:	NP_650507.1	Gene:	CG14877 / 41929	FlyBaseID:	FBgn0038380	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	XP_692173.5	Gene:	adcy2a / 563724	ZFINID:	ZDB-GENE-061109-1	Length:	1155	Species:	Danio rerio

Alignment Length:	150	Identity:	27/150 - (18%)
Similarity:	61/150 - (40%)	Gaps:	48/150 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 KSLIPSHIDFEWLAHDTKCD--------------ASLGVIKAM--------DGIIKQCAQVIFGP 117
            ::::|:|:...:||.:.|.:              ||:...|..        :|:  :|.:::...
Zfish   921 ENVLPAHVAEHFLARNWKNEDLYHQSYDLVCVMFASIPDFKEFYTESDVNKEGL--ECLRLLNEI 983

  Fly   118 VCDY-SLAAVSRITKYFNSQGTPLISVGGSTY------------DFEQKKTDCNDEFYMLLRTGM 169
            :.|: .|.:..:.:      |...|...||||            ::.|:    :|..||.:.| |
Zfish   984 IADFDELLSKPKFS------GVEKIKTIGSTYMAATGLNATPGPEYTQE----HDRQYMHIGT-M 1037

  Fly   170 LSFETISELTINVMKRHNWS 189
            :.|.......::|:.:|:::
Zfish  1038 VEFAFALVGKLDVINKHSFN 1057

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14877	NP_650507.1	Periplasmic_Binding_Protein_Type_1	46..>241	CDD:299141	27/149 (18%)
adcy2a	XP_692173.5	AC_N	<92..319	CDD:292831
		CYCc	295..498	CDD:214485
		Guanylate_cyc	340..524	CDD:278633
		DUF1053	554..658	CDD:283888
		CYCc	912..1120	CDD:214485	27/149 (18%)
		Guanylate_cyc	942..1141	CDD:278633	22/128 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900