DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14877 and adcy6b

DIOPT Version :9

Sequence 1:	NP_650507.1	Gene:	CG14877 / 41929	FlyBaseID:	FBgn0038380	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	XP_002666536.2	Gene:	adcy6b / 560807	ZFINID:	ZDB-GENE-090127-2	Length:	1174	Species:	Danio rerio

Alignment Length:	244	Identity:	43/244 - (17%)
Similarity:	91/244 - (37%)	Gaps:	76/244 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 TIRALVLLPDDNMYQ---------ASLPRVLPILKVA----EQQIRSKSLIPSHIDFEWLAHDTK 92
            |:.||....:.|..|         .|:|.:|.:..:|    .||:.|    .:.:||.|....|:
Zfish   877 TVDALYAFNETNYCQETVTKVSLRVSIPVILTVFVLALYLHAQQVES----TARLDFLWKLQATE 937

  Fly    93 CDASLGVIKA-----MDGIIK----------------------QCAQVIFGPVCDYSLAAVSRIT 130
            ....:..::|     :..|:.                      :|..|:|        |::|..:
Zfish   938 EKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMF--------ASISNFS 994

  Fly   131 KYF-----NSQGTPLISVGGSTY-DFEQKKTDCNDEFYMLLRTGMLSFETISELTINVMKRHNWS 189
            :::     |::|...:.:..... ||::   ..::|.|..|       |.|..:....|.....:
Zfish   995 EFYTELEANNEGVECLRLLNEIIADFDE---IISEEKYKQL-------EKIKTIGSTYMAASGLN 1049

  Fly   190 HSIFYYERDGQRSVAGMHTCFLMMKSLGKQMR--NENMTFAQFPLEPNL 236
            .|.  |:::|:..:..:....:.::   :||:  ||: :|..|.::..|
Zfish  1050 DST--YDKEGRTHILALADYAMRLR---EQMKYINEH-SFNNFQMKIGL 1092

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14877	NP_650507.1	Periplasmic_Binding_Protein_Type_1	46..>241	CDD:299141	40/239 (17%)
adcy6b	XP_002666536.2	AC_N	15..376	CDD:318454
		Guanylate_cyc	378..562	CDD:306677
		DUF1053	590..677	CDD:310728
		Guanylate_cyc	975..1169	CDD:306677	25/142 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900