DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14877 and si:ch211-132f19.7

DIOPT Version :9

Sequence 1:	NP_650507.1	Gene:	CG14877 / 41929	FlyBaseID:	FBgn0038380	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	XP_688903.4	Gene:	si:ch211-132f19.7 / 560410	ZFINID:	ZDB-GENE-130530-619	Length:	1183	Species:	Danio rerio

Alignment Length:	287	Identity:	56/287 - (19%)
Similarity:	100/287 - (34%)	Gaps:	101/287 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 ATCREEPARDCEAICDAN---GRNCTIRALVLLPD----------DNMYQAS----------LPR 60
            :||..   :..|::.||:   ....|:|. :.||.          :::||..          :..
Zfish    99 STCTR---KSTESVTDADFFVSWGSTVRG-IFLPALHHKFKSHDLEHLYQQHSSGQRRTSLVVTN 159

  Fly    61 VLPILKVAEQQIRSKSLIPSHIDFE--WLAHDTKCDASLGVIKAMDGIIKQCAQVIFGPVC---- 119
            |:.||..........:|.|..:|.:  |||         |::.|:..||  |..|:   .|
Zfish   160 VIDILTKLHIIFIYLALAPEMVDSQHGWLA---------GLLMALGAII--CVLVL---TCKGLM 210

  Fly   120 --DY----SLAA-VSRITKYFNSQGTPLISVGGSTYDFEQKKTDCNDEFYM-------------- 163
              ||    .||: :|:..:          ::||..|..|   ||  ..:|:
Zfish   211 SPDYLRYAGLASWLSQTVQ----------ALGGLVYGLE---TD--QSWYVLFTLFAIYTLLPLP 260

  Fly   164 LLRTGMLSFETIS-ELTINVMKRHN--------WSHSIFYYERDGQRSVAGMHTCFLMMKSLGKQ 219
            ||.:..:.|.|.: .|.::..|.:|        .:..:.|         .||:|..|.:..|..:
Zfish   261 LLWSICMGFLTAALHLFVDTFKNYNDTAIVRKLLAKGLLY---------MGMNTAGLFIHYLSDR 316

  Fly   220 MRNENMTFAQFPLEPNLTNRTEEMRRE 246
            .:.:.....:..:|..:....|..|:|
Zfish   317 AQRQAFLETRRCIEGRVKMERENQRQE 343

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14877	NP_650507.1	Periplasmic_Binding_Protein_Type_1	46..>241	CDD:299141	46/250 (18%)
si:ch211-132f19.7	XP_688903.4	AC_N	<133..375	CDD:292831	47/249 (19%)
		CYCc	338..537	CDD:214485	3/6 (50%)
		Guanylate_cyc	381..559	CDD:278633
		DUF1053	579..667	CDD:283888
		CYCc	903..1103	CDD:214485
		Guanylate_cyc	932..1131	CDD:278633
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900