DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14877 and adcy2b

DIOPT Version :9

Sequence 1:	NP_650507.1	Gene:	CG14877 / 41929	FlyBaseID:	FBgn0038380	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	XP_005170095.1	Gene:	adcy2b / 557902	ZFINID:	ZDB-GENE-060503-69	Length:	1142	Species:	Danio rerio

Alignment Length:	143	Identity:	30/143 - (20%)
Similarity:	47/143 - (32%)	Gaps:	50/143 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 HDTKCDASLGVIKAMDGIIKQCAQVIFGPVCDYSLAAVSR-------ITKYFNSQG--------- 137
            ::.|....||.:.|.:.||.|....|..   |||:|....       :.|...:.|
Zfish   805 YELKMIIMLGAVVAYNIIILQTHASILD---DYSMALYKTQQPDRPGVLKDLKTMGSISLFIFFV 866

  Fly   138 TPLISVGGSTY----DF---EQKKTDCNDEFYMLLRTGMLSFETISELT----INVMKRH----- 186
            |.|:....:.|    ||   .:.|.:|.:            .||:..|.    .||:..|
Zfish   867 TLLVLARQNEYYCRLDFLWRNKFKKECEE------------IETMENLNRVLLENVLPAHVAEHF 919

  Fly   187 ---NWSHSIFYYE 196
               ||.:...|::
Zfish   920 LGRNWKNEDLYHQ 932

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14877	NP_650507.1	Periplasmic_Binding_Protein_Type_1	46..>241	CDD:299141	30/143 (21%)
adcy2b	XP_005170095.1	AC_N	<80..307	CDD:292831
		CYCc	283..486	CDD:214485
		Guanylate_cyc	328..512	CDD:278633
		DUF1053	542..646	CDD:283888
		CYCc	899..1106	CDD:214485	7/34 (21%)
		Guanylate_cyc	929..1128	CDD:278633	1/4 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900