DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14877 and gucy1a1

DIOPT Version :9

Sequence 1:	NP_650507.1	Gene:	CG14877 / 41929	FlyBaseID:	FBgn0038380	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_001296458.1	Gene:	gucy1a1 / 550420	ZFINID:	ZDB-GENE-050417-230	Length:	679	Species:	Danio rerio

Alignment Length:	160	Identity:	36/160 - (22%)
Similarity:	57/160 - (35%)	Gaps:	51/160 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 EEPARDCEAICDANGRNCTIRALVLLPDDNMYQASLPRVLPILKVAEQQIRSKSL--------IP 79
            ||||       |..|.|    |:.::|.....|.::..:||..|::..::...||        .|
Zfish    24 EEPA-------DFEGSN----AVNVVPVSREVQGNITNILPRRKISRSKVNLHSLGESVRKLVCP 77

  Fly    80 SHIDFEWLAH----------DTKCD--ASLGVIKAMDGIIKQCAQVIFGPVCDYSL--------- 123
               :||.|.:          ||.|.  .|..|...:|.     |:.:...:.:|||
Zfish    78 ---EFEKLRNALIRVIKQQIDTSCPVACSSDVSHTLDN-----AEQLSDVMKNYSLKTGIPMDAL 134

  Fly   124 ---AAVSRITKYFNSQGTPLISVGGSTYDF 150
               ..:......:...|..|..|||:.:||
Zfish   135 KISLGLEVFRDCYEEDGHILRVVGGALHDF 164

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14877	NP_650507.1	Periplasmic_Binding_Protein_Type_1	46..>241	CDD:299141	28/137 (20%)
gucy1a1	NP_001296458.1	HNOBA	279..470	CDD:285003
		CYCc	449..635	CDD:214485
		Guanylate_cyc	476..647	CDD:278633
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900