DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG14877 and NPR1

DIOPT Version :10

Sequence 1:NP_650507.1 Gene:CG14877 / 41929 FlyBaseID:FBgn0038380 Length:254 Species:Drosophila melanogaster
Sequence 2:NP_000897.3 Gene:NPR1 / 4881 HGNCID:7943 Length:1061 Species:Homo sapiens


Alignment Length:262 Identity:61/262 - (23%)
Similarity:109/262 - (41%) Gaps:60/262 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MLLVLLLVGLVFGPKDCVATCREEPARDCEAICDANGRNCTIRALVLLPDDNMYQASLPRVLPIL 65
            :||:|||..|:.                  .:..::..|.|: |:||...:..|..|..||.|.:
Human    14 LLLLLLLPPLLL------------------LLRGSHAGNLTV-AVVLPLANTSYPWSWARVGPAV 59

  Fly    66 KVAEQQIRSK-SLIPSHIDFEWLAHDT--KCDASLGV-------IKAMDGIIKQCAQVIFGPVCD 120
            ::|..|:::: .|:|.     |.....  ..:.:|||       :.|:|...:....|..||.|.
Human    60 ELALAQVKARPDLLPG-----WTVRTVLGSSENALGVCSDTAAPLAAVDLKWEHNPAVFLGPGCV 119

  Fly   121 YSLAAVSRITKYFNSQGTPLISVGGSTYDFEQKKTDCNDEFYMLLRTGMLSFETISELTINVMKR 185
            |:.|.|.|.|.::.   .||::.|.....|..|     ||:.:..|.|. |:..:.:....:.:|
Human   120 YAAAPVGRFTAHWR---VPLLTAGAPALGFGVK-----DEYALTTRAGP-SYAKLGDFVAALHRR 175

  Fly   186 HNWSHS--IFYYERDGQRSVAGMHTCFLMMKSLGKQMRN------ENMTFAQFPLEPNLTNRTEE 242
            ..|...  :.|..|.|...    | ||.:::.|..::|:      :::.||    |.:|::.|..
Human   176 LGWERQALMLYAYRPGDEE----H-CFFLVEGLFMRVRDRLNITVDHLEFA----EDDLSHYTRL 231

  Fly   243 MR 244
            :|
Human   232 LR 233

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG14877NP_650507.1 Periplasmic_Binding_Protein_type1 45..>251 CDD:471960 52/218 (24%)
NPR1NP_000897.3 PBP1_NPR_A 36..443 CDD:380608 54/222 (24%)
PK_GC-A_B 534..807 CDD:270944
HNOBA <813..861 CDD:462234
CYCc 840..1032 CDD:214485
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.