DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14877 and CG43373

DIOPT Version :9

Sequence 1:	NP_650507.1	Gene:	CG14877 / 41929	FlyBaseID:	FBgn0038380	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_001097622.2	Gene:	CG43373 / 39835	FlyBaseID:	FBgn0263131	Length:	1854	Species:	Drosophila melanogaster

Alignment Length:	156	Identity:	29/156 - (18%)
Similarity:	52/156 - (33%)	Gaps:	62/156 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly   122 SLAAVSRITKYFNSQGTPL---------ISVGGS---------TYDFEQKKTDCNDEFYMLLRT- 167
            :|..::.:...|...|..:         :.|.||         |..::.::.||  :||:...|
  Fly  1088 ALIVLTTLLAMFQESGRQMELLQRRRFWLDVNGSISLNDTELNTKMYDAEEPDC--DFYLAYNTF 1150

  Fly   168 ------GMLSFETISELTINVMKRHNWSHSIFYYERDGQRSVAGMHTCFLMMKSLGKQMRNENMT 226
                  .|:|..|...|.| ::|                        ..|::.:.|..|
  Fly  1151 LLLTLLSMMSCATYQVLRI-LLK------------------------LLLLLLASGSYM------ 1184

  Fly   227 FAQFPLEPNLTNRTEEMRREIGNKHA 252
                ....||.:|:.||.:|:.|:.|
  Fly  1185 ----ACSSNLYSRSREMSQELANEEA 1206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14877	NP_650507.1	Periplasmic_Binding_Protein_Type_1	46..>241	CDD:299141	24/143 (17%)
CG43373	NP_001097622.2	AC_N	<523..720	CDD:292831
		CYCc	686..881	CDD:214485
		Guanylate_cyc	722..895	CDD:278633
		DUF1053	<949..1005	CDD:283888
		CYCc	1259..1455	CDD:214485
		Guanylate_cyc	1285..1479	CDD:278633
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900