DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14877 and CG33958

DIOPT Version :9

Sequence 1:	NP_650507.1	Gene:	CG14877 / 41929	FlyBaseID:	FBgn0038380	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_001033958.1	Gene:	CG33958 / 37088	FlyBaseID:	FBgn0053958	Length:	710	Species:	Drosophila melanogaster

Alignment Length:	236	Identity:	50/236 - (21%)
Similarity:	89/236 - (37%)	Gaps:	64/236 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 PRVLPILKVAEQQIRSKSLIPSHIDFEWLAHDTKCDASLGVI----KAMDGIIKQCAQVIFGPVC 119
            |.::.::|.|...|:..:|..|....|......|.|:.|..:    .||.  :||..||   |..
  Fly   429 PVIIVLVKNAAATIQLYALNLSQKAKELKREKRKSDSLLFQMLPPSVAMQ--LKQTQQV---PAE 488

  Fly   120 DYSLAAVSRITKYFN---------SQGTPL--ISVGGSTYDFEQKKTDCNDEF--------YML- 164
            .|     ..:|.||:         :..|||  ::...|.|....::.:|.|.:        ||:
  Fly   489 LY-----EAVTIYFSDIVGFTEIAADCTPLEVVTFLNSIYRVFDERIECYDVYKVETIGDSYMVA 548

  Fly   165 ----LRTGMLSFETISELTINVMKRHNWSHSIFYYERDGQRSV---AGMHTCFLMMKSLGKQMRN 222
                ::.|......|:.:.::::.    :.|:|...|.|...|   .|:||..::...:|.:|..
  Fly   549 SGLPVKNGNKHISEIATMALDLLD----ASSVFRIPRAGDEFVQIRCGVHTGPVVAGIVGTKMPR 609

  Fly   223 ENMTFAQFPLEPNLTNR------------TEEMR---REIG 248
                :..|....|..:|            ||||.   :::|
  Fly   610 ----YCLFGDTVNTASRMESTGEAQKIHITEEMHDSLQQVG 646

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14877	NP_650507.1	Periplasmic_Binding_Protein_Type_1	46..>241	CDD:299141	45/224 (20%)
CG33958	NP_001033958.1	NIT	159..396	CDD:285564
		HNOBA	<439..479	CDD:285003	9/41 (22%)
		CYCc	459..647	CDD:214485	43/206 (21%)
		Guanylate_cyc	485..669	CDD:278633	35/178 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900