DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14877 and GUCY2F

DIOPT Version :9

Sequence 1:	NP_650507.1	Gene:	CG14877 / 41929	FlyBaseID:	FBgn0038380	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_001513.2	Gene:	GUCY2F / 2986	HGNCID:	4691	Length:	1108	Species:	Homo sapiens

Alignment Length:	150	Identity:	34/150 - (22%)
Similarity:	56/150 - (37%)	Gaps:	34/150 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 DNMYQASLPRVLPILKVAEQQIRSKSLIPSHIDFEWLAHDTKCDASLGVIKAMDGIIK--QCAQV 113
            |:::..:||.|...|.: |:..|..|...|: .||::..:..|..|    :|:...|.  |.|..
Human    64 DSLFSKALPEVAARLAI-ERINRDPSFDLSY-SFEYVILNEDCQTS----RALSSFISHHQMASG 122

  Fly   114 IFGPVCDYSLAAVSRITKYFNSQGTPLISVGGSTYDFEQKKTDCNDEFYMLLRTGMLSFETIS-- 176
            ..||.......|.|.:.   ||....:.|.....|:.:.|                :|:.|.|
Human   123 FIGPTNPGYCEAASLLG---NSWDKGIFSWACVNYELDNK----------------ISYPTFSRT 168

  Fly   177 -----ELTINVMKRHNWSHS 191
                 .:.:.|||...|:|:
Human   169 LPSPIRVLVTVMKYFQWAHA 188

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14877	NP_650507.1	Periplasmic_Binding_Protein_Type_1	46..>241	CDD:299141	34/149 (23%)
GUCY2F	NP_001513.2	PBP1_sensory_GC_DEF_like	54..435	CDD:107366	34/149 (23%)
		ANF_receptor	75..412	CDD:279440	30/138 (22%)
		PKc_like	545..815	CDD:304357
		HNOBA	<824..869	CDD:285003
		CYCc	848..1040	CDD:214485
		Guanylate_cyc	875..1062	CDD:278633
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810